Compile Data Set for Download or QSAR

Found 19 hits of Enzyme Inhibition Constant Data   

TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243428(1-((3R,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243427(1-((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243425(1-((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243375(CHEMBL451765 | N-((3S,5S)-5-(((R)-1-(3,5-bis(trifl...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243376(CHEMBL452532 | N-((3R,5S)-5-(((R)-1-(3,5-bis(trifl...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243337(CHEMBL452270 | N-((3S,5S)-5-(((R)-1-(3,5-bis(trifl...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243476((5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)eth...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243474((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243475((5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)eth...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243426(1-((3R,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177387((R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)etho...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243373(CHEMBL451763 | N-((3S,5S)-5-(((R)-1-(3,5-bis(trifl...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243264((S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)etho...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243335((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243338(CHEMBL452271 | N-((3R,5S)-5-(((R)-1-(3,5-bis(trifl...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243336((3R,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243374(CHEMBL451764 | N-((3R,5S)-5-(((R)-1-(3,5-bis(trifl...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]Sar-Met substance P from human recombinant NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243425(1-((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  1.25E+3nMAssay Description:Displacement of [125I]Neurokinin B from human recombinant NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50243264((S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)etho...)copy SMILEScopy InChI
Affinity DataKi:  3.82E+3nMAssay Description:Displacement of [125I]Neurokinin B from human recombinant NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79B7FPubMed
* indicates data uncertainty>20%