Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Lund University

Curated by ChEMBL
LigandPNGBDBM50293263(2-(5-benzyl-2-hydroxyphenyl)-6-methyl-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha1beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Lund University

Curated by ChEMBL
LigandPNGBDBM50293262(2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha1beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
Lund University

Curated by ChEMBL
LigandPNGBDBM50293263(2-(5-benzyl-2-hydroxyphenyl)-6-methyl-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha5beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
Lund University

Curated by ChEMBL
LigandPNGBDBM50293262(2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...)copy SMILEScopy InChI
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha5beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(RAT)
Lund University

Curated by ChEMBL
LigandPNGBDBM50293263(2-(5-benzyl-2-hydroxyphenyl)-6-methyl-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha3beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Lund University

Curated by ChEMBL
LigandPNGBDBM50293262(2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha2beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Lund University

Curated by ChEMBL
LigandPNGBDBM50293263(2-(5-benzyl-2-hydroxyphenyl)-6-methyl-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha2beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(RAT)
Lund University

Curated by ChEMBL
LigandPNGBDBM50293262(2-(5-benzyl-2-hydroxyphenyl)-6-methylquinolin-4(1H...)copy SMILEScopy InChI
Affinity DataKi:  31nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha3beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Lund University

Curated by ChEMBL
LigandPNGBDBM50293264(2-(5-bromo-2-hydroxyphenyl)-6-methylquinolin-4(1H)...)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha1beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3(RAT)
Lund University

Curated by ChEMBL
LigandPNGBDBM50293264(2-(5-bromo-2-hydroxyphenyl)-6-methylquinolin-4(1H)...)copy SMILEScopy InChI
Affinity DataKi:  99nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha3beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Lund University

Curated by ChEMBL
LigandPNGBDBM50293264(2-(5-bromo-2-hydroxyphenyl)-6-methylquinolin-4(1H)...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Displacement of [3H]flumazenil in rat GABAAalpha2beta3gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9Q3ZPubMed
* indicates data uncertainty>20%