Compile Data Set for Download or QSAR

Found 6 hits of Enzyme Inhibition Constant Data   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Research Institute, Hospital for Sick Children

LigandPNGBDBM84610(5-(3,5-dichlorophenoxy)-N-(4-pyrdinyl)-2- furamide...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ0ZJKPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Research Institute, Hospital for Sick Children

LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ0ZJKPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Research Institute, Hospital for Sick Children

LigandPNGBDBM84609(7,8-diethoxy-quinazoline 2,4-diamine, 1b)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ0ZJKPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Research Institute, Hospital for Sick Children

LigandPNGBDBM84608(2,4-diamino-6-nitro-quinazoline, 1a)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ0ZJKPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Research Institute, Hospital for Sick Children

LigandPNGBDBM84611(2-methyl-N-pyridin-4-yl-benzamide, 2a)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ0ZJKPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Research Institute, Hospital for Sick Children

LigandPNGBDBM84612(2,2-dimethyl-N-(4-pyridinyl)propanamide, 2b)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMpH: 5.5 T: 2°CAssay Description:Beta-glucocerebrosidase (GCase) activity was measured by release of 4-methylumbelliferyl fluorophore from MUClc.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ0ZJKPubMed
* indicates data uncertainty>20%