Compile Data Set for Download or QSAR

Found 39 hits of Enzyme Inhibition Constant Data   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246298(CHEMBL487067 | N-(2-hydroxyethyl)-4-(4-(1-isopropy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246301(4-(4-(1-cyclopentyl-2-methyl-1H-imidazol-5-yl)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246350(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246447(2-fluoro-4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246255(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246349(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246254(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246397(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246256(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246448(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246297(CHEMBL487066 | N-cyclopropyl-4-(4-(1-isopropyl-2-m...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246300(4-(4-(1-(cyclopropylmethyl)-2-methyl-1H-imidazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246299(4-(4-(1-ethyl-2-methyl-1H-imidazol-5-yl)pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase-like 1 [2-358](Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246347(4-(4-(1-isopropyl-2-(methoxymethyl)-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246346(4-(4-(2-cyclopropyl-1-isopropyl-1H-imidazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246397(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246253(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(me...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246447(2-fluoro-4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246297(CHEMBL487066 | N-cyclopropyl-4-(4-(1-isopropyl-2-m...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Zap70 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Csk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246395(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246350(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246349(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246396(2-fluoro-4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246254(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246256(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246399(2-fluoro-4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246398(2-fluoro-4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-im...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246348(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246255(4-(4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimi...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246298(CHEMBL487067 | N-(2-hydroxyethyl)-4-(4-(1-isopropy...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246448(4-(5-fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2377PubMed
* indicates data uncertainty>20%