Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26339((2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26347((2R,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26338((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 0.710nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26340((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26341((2E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26345((2R,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26346((2S,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26342((2E,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26348((2R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 240nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26344((2S,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)copy SMILEScopy InChI
Affinity DataIC50: 380nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Kyoto University

LigandPNGBDBM26343((2E,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)copy SMILEScopy InChI
Affinity DataIC50: 460nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TTPPubMed
* indicates data uncertainty>20%