Affinity Data by PubMed id=19014888

Found 52 hits of Enzyme Inhibition Constant Data

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI

Ki: 1.10nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed DrugBank

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI

Ki: 26nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254790((S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE)copy SMILEScopy InChI

Ki: 50nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254830(4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

Ki: 65nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI

Ki: 276nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254829(4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

Ki: 300nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI

Ki: 371nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI

Ki: 1.12E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI

Ki: 1.56E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254829(4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

Ki: 2.72E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI

Ki: 3.66E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254830(4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

Ki: 4.49E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254790((S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE)copy SMILEScopy InChI

Ki: 4.54E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254829(4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

Ki: 4.60E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254790((S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE)copy SMILEScopy InChI

Ki: 6.19E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254830(4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

Ki: 6.57E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI

Ki: 6.67E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI

Ki: 7.49E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30127(CHEMBL480988 | phthalazinone, 20)copy SMILEScopy InChI

Ki: 3.91E+4nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30127(CHEMBL480988 | phthalazinone, 20)copy SMILEScopy InChI

Ki: >1.00E+5nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30126(CHEMBL313041 | phthalazinone, 19)copy SMILEScopy InChI

Ki: >1.00E+5nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30126(CHEMBL313041 | phthalazinone, 19)copy SMILEScopy InChI

Ki: >1.00E+5nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30127(CHEMBL480988 | phthalazinone, 20)copy SMILEScopy InChI

Ki: >1.00E+5nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30126(CHEMBL313041 | phthalazinone, 19)copy SMILEScopy InChI

Ki: >1.00E+5nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30127(CHEMBL480988 | phthalazinone, 20)copy SMILEScopy InChI

IC50: 2.30nMAssay Description:Inhibition of PDE4D2 by rapid fluorescence based assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI

IC50: 7nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed DrugBank

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI

IC50: 13nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254829(4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 42nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254790((S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE)copy SMILEScopy InChI

IC50: 46nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254830(4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 106nMAssay Description:Inhibition of PDE4D2 by rapid fluorescence based assayMore data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254830(4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 173nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
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CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30126(CHEMBL313041 | phthalazinone, 19)copy SMILEScopy InChI

IC50: 213nMAssay Description:Inhibition of PDE4D2 by rapid fluorescence based assayMore data for this Ligand-Target Pair

PDB KEGG
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CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254829(4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 253nMAssay Description:Inhibition of PDE4D2 by rapid fluorescence based assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI

IC50: 303nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI

IC50: 416nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
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DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)copy SMILEScopy InChI

IC50: 835nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI

IC50: 1.02E+3nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI

IC50: 2.00E+3nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254790((S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE)copy SMILEScopy InChI

IC50: 2.81E+3nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254829(4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 5.98E+3nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254790((S)-Norfluoxetine | CHEMBL465123 | NORFLUOXETINE)copy SMILEScopy InChI

IC50: 6.49E+3nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254829(4-(3,4-dimethoxyphenyl)-2-(5-((S)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 6.55E+3nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254830(4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 6.81E+3nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254830(4-(3,4-dimethoxyphenyl)-2-(5-((R)-3-phenyl-3-(4-(t...)copy SMILEScopy InChI

IC50: 7.00E+3nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI

IC50: 7.13E+3nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI

IC50: 1.95E+4nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30126(CHEMBL313041 | phthalazinone, 19)copy SMILEScopy InChI

IC50: 1.00E+5nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30127(CHEMBL480988 | phthalazinone, 20)copy SMILEScopy InChI

IC50: 1.00E+5nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30126(CHEMBL313041 | phthalazinone, 19)copy SMILEScopy InChI

IC50: 1.00E+5nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

Sodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL

BDBM30126(CHEMBL313041 | phthalazinone, 19)copy SMILEScopy InChI

IC50: 1.00E+5nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed

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