Compile Data Set for Download or QSAR

Found 70 hits of Enzyme Inhibition Constant Data   

TargetInsulin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256480(CHEMBL466397 | N-(2,6-difluorophenyl)-5-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256480(CHEMBL466397 | N-(2,6-difluorophenyl)-5-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Binding affinity to IGF1R by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Binding affinity to IGF1R by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256467(CHEMBL448668 | N-(2,6-difluorophenyl)-3-(3-(2-(3-(...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256469((S)-N-(2,6-difluorophenyl)-3-(3-(2-(3-(3-(dimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256473(CHEMBL502198 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256475(CHEMBL449110 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256471(3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)-2-methoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256474((R)-N-(2,6-difluorophenyl)-3-(3-(2-(4-(4-(3-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256472(CHEMBL502652 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256410(CHEMBL447668 | N-(2,6-difluorophenyl)-3-(3-(2-(3-(...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256470(3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)phenylamino)pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256477(3-(3-(2-(4-(4-(4-acetylpiperazin-1-yl)piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256476(CHEMBL454796 | N-(2,6-difluorophenyl)-3-(3-(2-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256468(CHEMBL500003 | N-(2,6-difluorophenyl)-3-(3-(2-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged insulin receptor expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256466(CHEMBL444031 | N-(2,6-difluorophenyl)-3-(3-(2-(2,3...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256479(CHEMBL448929 | N-(2,6-difluorophenyl)-3-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged insulin receptor expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256479(CHEMBL448929 | N-(2,6-difluorophenyl)-3-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256470(3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)phenylamino)pyr...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256412(CHEMBL447450 | N-(2,6-difluorophenyl)-3-(3-(2-(3-(...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256480(CHEMBL466397 | N-(2,6-difluorophenyl)-5-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human insulin receptor autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256479(CHEMBL448929 | N-(2,6-difluorophenyl)-3-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256480(CHEMBL466397 | N-(2,6-difluorophenyl)-5-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256480(CHEMBL466397 | N-(2,6-difluorophenyl)-5-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of GST-tagged insulin receptor expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256480(CHEMBL466397 | N-(2,6-difluorophenyl)-5-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256465(CHEMBL480544 | N-(2,6-difluorophenyl)-3-(3-(2-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256475(CHEMBL449110 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256473(CHEMBL502198 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256471(3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)-2-methoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256474((R)-N-(2,6-difluorophenyl)-3-(3-(2-(4-(4-(3-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256472(CHEMBL502652 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256479(CHEMBL448929 | N-(2,6-difluorophenyl)-3-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256477(3-(3-(2-(4-(4-(4-acetylpiperazin-1-yl)piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256476(CHEMBL454796 | N-(2,6-difluorophenyl)-3-(3-(2-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256470(3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)phenylamino)pyr...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256471(3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)-2-methoxypheny...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256479(CHEMBL448929 | N-(2,6-difluorophenyl)-3-(3-(2-(5-e...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256468(CHEMBL500003 | N-(2,6-difluorophenyl)-3-(3-(2-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 174nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256467(CHEMBL448668 | N-(2,6-difluorophenyl)-3-(3-(2-(3-(...)copy SMILEScopy InChI
Affinity DataIC50: 177nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetAurora kinase B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256478(CHEMBL507714 | N-(2,6-difluorophenyl)-3-(3-(2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Aurora BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256469((S)-N-(2,6-difluorophenyl)-3-(3-(2-(3-(3-(dimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 244nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256412(CHEMBL447450 | N-(2,6-difluorophenyl)-3-(3-(2-(3-(...)copy SMILEScopy InChI
Affinity DataIC50: 247nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50256410(CHEMBL447668 | N-(2,6-difluorophenyl)-3-(3-(2-(3-(...)copy SMILEScopy InChI
Affinity DataIC50: 344nMAssay Description:Inhibition of human IGF1R autophosphorylation in transfected mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6J8MPubMed
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