Compile Data Set for Download or QSAR

Found 42 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276634(CHEMBL515193 | N-((1S)-3-(4-(3-(3,4-dichlorobenzyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.00300nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276450(CHEMBL460845 | N-((1S)-3-(4-(2-(3,4-dichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.0500nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276574(CHEMBL457043 | N-((1S)-3-(4-(N-ethyl-2-(4-(methyls...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276683(CHEMBL461687 | N-((1S)-3-(4-(3-benzyl-1-ethylureid...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276499(CHEMBL459384 | N-((1S)-3-(4-(2-(4-chlorophenyl)-N-...)copy SMILEScopy InChI
Affinity DataIC50: 0.340nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276500(CHEMBL456226 | N-((1S)-3-(4-(N-ethyl-2-(4-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276501(CHEMBL461690 | N-((1S)-3-(4-(N-ethyl-2-(4-fluoroph...)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276575(CHEMBL457044 | N-((1S)-3-(4-(2-(3-chlorophenyl)-N-...)copy SMILEScopy InChI
Affinity DataIC50: 1.54nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276091(CHEMBL469724 | N-((1S)-3-(4-(3-isopropyl-5-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276576(CHEMBL457960 | N-((1S)-3-(4-(2-(2,4-dichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.33nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276685(CHEMBL461689 | benzyl 1-((4S)-4-(cyclobutanecarbox...)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276686(4-chlorophenyl 1-((4S)-4-(cyclobutanecarboxamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276734(4-fluorophenyl 1-((4S)-4-(cyclobutanecarboxamido)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.63nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276577(CHEMBL458157 | N-((1S)-3-(4-(N-ethyl-2-p-tolylacet...)copy SMILEScopy InChI
Affinity DataIC50: 3.76nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276808(CHEMBL460009 | N-((1S)-3-(4-(2-oxo-4-phenyl-2,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276735(CHEMBL460628 | N-(1-((4S)-4-(cyclobutanecarboxamid...)copy SMILEScopy InChI
Affinity DataIC50: 4.83nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276449(CHEMBL518794 | N-((1S)-3-(4-(N-ethyl-2-(4-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276414((S)-4,4-difluoro-N-(3-(4-(3-isopropyl-5-methyl-4H-...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276631(CHEMBL514410 | N-((1S)-3-(4-(N-ethyl-2-phenylaceta...)copy SMILEScopy InChI
Affinity DataIC50: 13.4nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276447(CHEMBL456019 | N-((S)-3-((1R,3S,5S)-3-(N-ethyl-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276632(CHEMBL456224 | N-((1S)-3-(4-(N-ethyl-2-(2-methoxyp...)copy SMILEScopy InChI
Affinity DataIC50: 17.9nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276897(CHEMBL459599 | N-((1S)-3-(4-(3-methyl-1,2,4-oxadia...)copy SMILEScopy InChI
Affinity DataIC50: 21.4nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276736(4-chloro-N-(1-((4S)-4-(cyclobutanecarboxamido)-4-p...)copy SMILEScopy InChI
Affinity DataIC50: 25.3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276737(3,4-dichloro-N-(1-((4S)-4-(cyclobutanecarboxamido)...)copy SMILEScopy InChI
Affinity DataIC50: 33.7nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276090(CHEMBL469542 | N-((1S)-3-(4-(3,5-dimethyl-4H-1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 37.5nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276448((S)-N-(3-(4-(2-(4-methoxyphenyl)acetamido)piperidi...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276806(CHEMBL518326 | N-(1-((4S)-4-(cyclobutanecarboxamid...)copy SMILEScopy InChI
Affinity DataIC50: 64.4nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276807(CHEMBL460008 | N-(1-((4S)-4-(cyclobutanecarboxamid...)copy SMILEScopy InChI
Affinity DataIC50: 73.5nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276898(CHEMBL459600 | N-((1S)-3-(4-(3-isopropyl-1,2,4-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 94.6nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276809(CHEMBL460217 | N-((1S)-1-phenyl-3-(4-(4-(pyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276447(CHEMBL456019 | N-((S)-3-((1R,3S,5S)-3-(N-ethyl-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 248nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276809(CHEMBL460217 | N-((1S)-1-phenyl-3-(4-(4-(pyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 382nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276895(CHEMBL459598 | N-((1S)-3-(4-(5-((dimethylamino)met...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276090(CHEMBL469542 | N-((1S)-3-(4-(3,5-dimethyl-4H-1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 849nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276898(CHEMBL459600 | N-((1S)-3-(4-(3-isopropyl-1,2,4-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276896(CHEMBL516939 | N-((1S)-3-(4-(5-methyl-1,3,4-oxadia...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276808(CHEMBL460009 | N-((1S)-3-(4-(2-oxo-4-phenyl-2,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 2.31E+3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276895(CHEMBL459598 | N-((1S)-3-(4-(5-((dimethylamino)met...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276091(CHEMBL469724 | N-((1S)-3-(4-(3-isopropyl-5-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276684(CHEMBL461688 | N-((1S)-3-(4-(1-ethyl-3-methyl-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 6.43E+3nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50276633(CHEMBL456425 | N-((1S)-3-(4-(N-ethyl-2-methyl-2-ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 ex...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08VHPubMed
* indicates data uncertainty>20%