Compile Data Set for Download or QSAR

Found 30 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257737(CHEMBL444497 | methyl 2-(4-fluorophenyl)-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257690((E)-methyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]im...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257691((E)-isopropyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257734(2-(2,3-dimethylphenyl)-2-(4-(2-(3-(2-methyl-1H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257641(1-(8-(2-(1-(furan-2-ylmethyl)-4-phenylpiperidin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257731(2-(4-fluorophenyl)-2-(4-(3-fluorophenyl)-4-(2-(3-(...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257642(CHEMBL524050 | N-isopropyl-4-(2-(3-(2-methyl-1H-be...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257728((E)-N-((4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257733(2-(2,6-dimethylphenyl)-2-(4-(2-(3-(2-methyl-1H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257736(CHEMBL506273 | methyl 2-(4-(2-(3-(2-methyl-1H-benz...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257644(CHEMBL471149 | N-cyclohexyl-4-(2-(3-(2-methyl-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257643(CHEMBL445003 | N-tert-butyl-4-(2-(3-(2-methyl-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257732(2-(benzo[d][1,3]dioxol-5-yl)-2-(4-(2-(3-(2-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257730(2-(4-methoxyphenyl)-2-(4-(2-(3-(2-methyl-1H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257692((E)-cyclopentyl N-cyano-4-(2-(3-(2-methyl-1H-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257729(2-(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-a...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257727((Z)-N'-cyano-N-methyl-4-(2-(3-(2-methyl-1H-benzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257694((E)-isopropyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257738(CHEMBL500824 | methyl 2-(2,3-dimethylphenyl)-2-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257640(2-((4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257689(CHEMBL506788 | N,N-diisopropyl-4-(2-(3-(2-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257687(CHEMBL492544 | N,N-dimethyl-4-(2-(3-(2-methyl-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257693((E)-methyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]im...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257735(2-(5-chlorothiophen-2-yl)-2-(4-(2-(3-(2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257688(CHEMBL509179 | N,N-diethyl-4-(2-(3-(2-methyl-1H-be...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257695((E)-cyclopentyl N-cyano-4-(2-(3-(2-methyl-1H-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257537(1-(8-(2-(1-((1H-imidazol-2-yl)methyl)-4-phenylpipe...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257490(2-methyl-1-(8-(2-(4-phenyl-1-(1H-tetrazol-5-yl)pip...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257645(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azab...)copy SMILEScopy InChI
Affinity DataIC50: 265nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50257489(2-methyl-1-(8-(2-(4-phenyl-1-(pyrimidin-2-yl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 (unknown origin) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32JRPubMed
* indicates data uncertainty>20%