Compile Data Set for Download or QSAR

Found 47 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258090((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of CCR5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257995((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-et...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257898((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258043((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258090((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258143((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3,5-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258043((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257841((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257900((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258092((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257899((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257901((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257994((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258045((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257843((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257792((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(cycl...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257992((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257842((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258044((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-cy...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257791((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(cycl...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257840((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(cycl...)copy SMILEScopy InChI
Affinity DataIC50: 175nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257950((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(2,3-...)copy SMILEScopy InChI
Affinity DataIC50: 187nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257789((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(cycl...)copy SMILEScopy InChI
Affinity DataIC50: 193nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258093((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3,3-...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257951((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 239nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 259nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258046((1S,3R)-N-(3,5-bis(trifluoromethyl)benz yl)-3-(3-f...)copy SMILEScopy InChI
Affinity DataIC50: 259nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257790((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 362nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257993((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(chro...)copy SMILEScopy InChI
Affinity DataIC50: 419nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50257949((1S,3R)-3-(1,1-Dioxo-hexahydro-1lambda*6*-thiopyra...)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258091((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 765nMAssay Description:Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HVZPubMed
* indicates data uncertainty>20%