Compile Data Set for Download or QSAR

Found 30 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301016(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1,1-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301015(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301009(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMedDrugBank
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301017(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-((dimet...)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301013(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-((4-met...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301014(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(thiomo...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301012(4-(2,4-dichloro-5-methoxyphenylamino)-7-(6-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301019(4-(2,4-dichlorophenylamino)-7-(5-((4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301018(7-(5-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301010(4-(2,4-dichloro-5-methoxyphenylamino)-7-(6-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301008(4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301011(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301013(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-((4-met...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301015(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMedDrugBank
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301017(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-((dimet...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301020(4-(2,4-dichloro-5-methoxyphenylamino)-6-(5-((4-met...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301016(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1,1-d...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301009(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301014(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(thiomo...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301008(4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301012(4-(2,4-dichloro-5-methoxyphenylamino)-7-(6-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301018(7-(5-((4-methylpiperazin-1-yl)methyl)pyridin-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301019(4-(2,4-dichlorophenylamino)-7-(5-((4-methylpiperaz...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301010(4-(2,4-dichloro-5-methoxyphenylamino)-7-(6-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301007(4-(2,4-dichloro-5-methoxyphenylamino)-7-(3-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301011(4-(2,4-dichloro-5-methoxyphenylamino)-7-(5-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301020(4-(2,4-dichloro-5-methoxyphenylamino)-6-(5-((4-met...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301007(4-(2,4-dichloro-5-methoxyphenylamino)-7-(3-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M081RPubMed
* indicates data uncertainty>20%