Affinity Data by PubMed id=19654408

Found 2521 hits of Enzyme Inhibition Constant Data

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI

IC50: 2nMAssay Description:Inhibition of FLT3 autophosphorylation in human AML cells isolated from relapsed acute myeloid leukemia patient by Western blottingMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

IC50: 2.60nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI

IC50: 3.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI

IC50: 4.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI

IC50: 9.90nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

IC50: 15nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)copy SMILEScopy InChI

IC50: 170nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326054(CHEMBL1240703)copy SMILEScopy InChI

IC50: 350nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Homeodomain-interacting protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 3.10E+3nMAssay Description:Binding affinity to HIPK2More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Protein kinase C delta type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 320nMAssay Description:Binding affinity to PRKCDMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to IGF1RMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Serine/threonine-protein kinase Nek7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 4.00E+3nMAssay Description:Binding affinity to NEK7More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Ephrin type-A receptor 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA6More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

STE20-like serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 35nMAssay Description:Binding affinity to SLKMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Protein kinase C alpha type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Serine/threonine-protein kinase TNNI3K(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to TNNI3KMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI

Kd: 410nMAssay Description:Binding affinity to MLCKMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Mitogen-activated protein kinase kinase kinase 15(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 3.40nMAssay Description:Binding affinity to MAP3K15More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK3CDMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Dual specificity protein kinase CLK4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 3nMAssay Description:Binding affinity to CLK4More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Serine/threonine-protein kinase Chk2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 210nMAssay Description:Binding affinity to CHEK2More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Tyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 680nMAssay Description:Binding affinity to TIE1More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Interleukin-1 receptor-associated kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to IRAK3More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 12nMAssay Description:Binding affinity to MLCKMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Mitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 23nMAssay Description:Binding affinity to MAP4K4More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Casein kinase I isoform gamma-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK1G1More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

cAMP-dependent protein kinase catalytic subunit PRKX(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 960nMAssay Description:Binding affinity to PRKXMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Insulin receptor-related protein(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to INSRRMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

SRSF protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 330nMAssay Description:Binding affinity to SRPK2More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Serine/threonine-protein kinase 36(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to STK36More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

SRSF protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to SRPK3More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Dual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to MEK6More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Serine/threonine-protein kinase D3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 8.90nMAssay Description:Binding affinity to PRKD3More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Rho-associated protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 71nMAssay Description:Binding affinity to ROCK2More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Macrophage-stimulating protein receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 8.20E+3nMAssay Description:Binding affinity to MST1RMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

LIM domain kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to LIMK2More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Ephrin type-A receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326054(CHEMBL1240703)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA1More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Inhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 3.80E+3nMAssay Description:Binding affinity to IKK-alphaMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Dual specificity protein kinase CLK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 350nMAssay Description:Binding affinity to CLK1More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Mitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 2.80E+3nMAssay Description:Binding affinity to LZKMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Hormonally up-regulated neu tumor-associated kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 240nMAssay Description:Binding affinity to HUNKMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Rhodopsin kinase GRK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 85nMAssay Description:Binding affinity to GRK1More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Macrophage-stimulating protein receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to MST1RMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Interleukin-1 receptor-associated kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: 180nMAssay Description:Binding affinity to IRAK3More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Myosin-IIIb(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to MYO3BMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Cyclin-dependent kinase 17(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to PCTK2More data for this Ligand-Target Pair

KEGG
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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Uncharacterized serine/threonine-protein kinase SBK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI

Kd: >1.00E+4nMAssay Description:Binding affinity to SgK110More data for this Ligand-Target Pair

KEGG
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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 4.20E+3nMAssay Description:Binding affinity to IGF1RMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Ribosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI

Kd: 2.40E+3nMAssay Description:Binding affinity to RPS6KA6(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Serine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI

Kd: 24nMAssay Description:Binding affinity to PAK4More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed

Displayed 1 to 50 (of 2521 total ) | Next | Last >>* indicates data uncertainty>20%

Targets 346 ▿
- Receptor-type tyrosine-protein kinase FLT3 22
- Ribosomal protein S6 kinase alpha-2 14
- Ribosomal protein S6 kinase alpha-1 14
- Ephrin type-A receptor 6 14
- Non-receptor tyrosine-protein kinase TYK2 14
- Mitogen-activated protein kinase 14 14
- Myosin light chain kinase, smooth muscle 14
- Tyrosine-protein kinase JAK1 14
- Serine/threonine-protein kinase TAO1 14
- Ribosomal protein S6 kinase alpha-6 14
- Calcium/calmodulin-dependent protein kinase type II subunit gamma 14
- Ribosomal protein S6 kinase alpha-4 14
- Ribosomal protein S6 kinase alpha-5 14
- Tyrosine-protein kinase Tec 7
- BMP-2-inducible protein kinase 7
- Rhodopsin kinase GRK1 7
- Cyclin-dependent kinase 11B 7
- Cyclin-dependent kinase 11A 7
- Uncharacterized serine/threonine-protein kinase SBK3 7
- LIM domain kinase 1 7
- LIM domain kinase 2 7
- ALK tyrosine kinase receptor 7
- NUAK family SNF1-like kinase 2 7
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 7
- Glycogen synthase kinase-3 beta 7
- Calcium/calmodulin-dependent protein kinase type 1 7
- NUAK family SNF1-like kinase 1 7
- AP2-associated protein kinase 1 7
- Calcium/calmodulin-dependent protein kinase type II subunit beta 7
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 7
- Serine/threonine-protein kinase PAK 1 7
- Protein kinase C theta type 7
- Serine/threonine-protein kinase PAK 2 7
- Serine/threonine-protein kinase PAK 3 7
- Dual specificity mitogen-activated protein kinase kinase 2 7
- Serine/threonine-protein kinase PAK 4 7
- Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 7
- Serine/threonine-protein kinase tousled-like 2 7
- Dual specificity mitogen-activated protein kinase kinase 3 7
- Serine/threonine-protein kinase PAK 5 7
- Serine/threonine-protein kinase PAK 6 7
- Serine/threonine-protein kinase tousled-like 1 7
- Tyrosine-protein kinase JAK3 7
- Tyrosine-protein kinase JAK2 7
- Dual specificity mitogen-activated protein kinase kinase 1 7
- Protein delta homolog 1 7
- Dual specificity mitogen-activated protein kinase kinase 6 7
- Dual specificity mitogen-activated protein kinase kinase 4 7
- Tyrosine-protein kinase ZAP-70 7
- Casein kinase I isoform gamma-3 7
- Casein kinase I isoform gamma-2 7
- Casein kinase I isoform epsilon 7
- Casein kinase I isoform gamma-1 7
- Ephrin type-A receptor 1 7
- Ephrin type-A receptor 3 7
- Ephrin type-A receptor 2 7
- Ephrin type-A receptor 5 7
- Tyrosine-protein kinase BTK 7
- Ephrin type-A receptor 4 7
- Tyrosine-protein kinase receptor UFO 7
- Insulin-like growth factor 1 receptor 7
- Activin receptor type-1 7
- Myosin light chain kinase 2, skeletal/cardiac muscle 7
- Tyrosine-protein kinase Srms 7
- Wee1-like protein kinase 7
- U4/U6 small nuclear ribonucleoprotein Prp4 7
- Serine/threonine-protein kinase/endoribonuclease IRE1 7
- Serine/threonine-protein kinase MAK 7
- Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma 7
- Ankyrin repeat and protein kinase domain-containing protein 1 7
- Tyrosine-protein kinase Lyn 7
- Focal adhesion kinase 1 7
- Cyclin-dependent kinase 2 7
- Tyrosine-protein kinase TXK 7
- Rhodopsin kinase GRK7 7
- Ephrin type-A receptor 8 7
- Phosphatidylinositol 4-kinase beta 7
- Death-associated protein kinase 2 7
- Death-associated protein kinase 1 7
- Serine/threonine-protein kinase D2 7
- Serine/threonine-protein kinase D3 7
- TGF-beta receptor type-2 7
- Serine/threonine-protein kinase D1 7
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B 7
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 7
- Death-associated protein kinase 3 7
- Cyclin-dependent kinase 9 7
- Serine/threonine-protein kinase pim-3 7
- Cyclin-dependent kinase 8 7
- Cyclin-dependent kinase 7 7
- Serine/threonine-protein kinase pim-1 7
- Cyclin-dependent kinase 5 7
- Serine/threonine-protein kinase pim-2 7
- Serine/threonine-protein kinase 38 7
- Serine/threonine-protein kinase 35 7
- Cyclin-dependent kinase 3 7
- Serine/threonine-protein kinase 36 7
- Cyclin-dependent kinase 16 7
- Testis-specific serine/threonine-protein kinase 1 7
- Protein kinase C epsilon type 7
- Cyclin-dependent kinase 17 7
- Bone morphogenetic protein receptor type-2 7
- Cyclin-dependent kinase 19 7
- Protein-tyrosine kinase 6 7
- Casein kinase II subunit alpha 7
- Cyclin-dependent kinase 14 7
- Cyclin-dependent kinase 15 7
- Leukocyte tyrosine kinase receptor 7
- Cytoplasmic tyrosine-protein kinase BMX 7
- Tyrosine-protein kinase ABL2 7
- Tyrosine-protein kinase ABL1 7
- Atypical kinase COQ8B, mitochondrial 7
- Microtubule-associated serine/threonine-protein kinase 1 7
- Calcium/calmodulin-dependent protein kinase type II subunit alpha 7
- cGMP-dependent protein kinase 2 7
- Rho-associated protein kinase 2 7
- cGMP-dependent protein kinase 1 7
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 7
- Rho-associated protein kinase 1 7
- Serine/threonine-protein kinase ULK1 7
- Serine/threonine-protein kinase SIK2 7
- Tyrosine-protein kinase Fes/Fps 7
- Serine/threonine-protein kinase SIK1 7
- Serine/threonine-protein kinase ULK2 7
- Serine/threonine-protein kinase ULK3 7
- 3-phosphoinositide-dependent protein kinase 1 7
- Mitogen-activated protein kinase 1 7
- Serine/threonine-protein kinase 3 7
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 7
- Mitogen-activated protein kinase 3 7
- Discoidin domain-containing receptor 2 7
- Mitogen-activated protein kinase 4 7
- Serine/threonine-protein kinase 4 7
- SRSF protein kinase 3 7
- Mitogen-activated protein kinase 9 7
- SRSF protein kinase 2 7
- Mitogen-activated protein kinase 6 7
- Mitogen-activated protein kinase 7 7
- Calcium/calmodulin-dependent protein kinase type IV 7
- Mitogen-activated protein kinase 8 7
- Tyrosine-protein kinase SYK 7
- Serine/threonine-protein kinase TBK1 7
- Serine/threonine-protein kinase RIO1 7
- Serine/threonine-protein kinase LATS1 7
- Serine/threonine-protein kinase RIO3 7
- Serine/threonine-protein kinase 32B 7
- Serine/threonine-protein kinase RIO2 7
- Serine/threonine-protein kinase 32C 7
- Vascular endothelial growth factor receptor 2 7
- Insulin receptor 7
- Tyrosine-protein kinase HCK 7
- Vascular endothelial growth factor receptor 3 7
- Vascular endothelial growth factor receptor 1 7
- Serine/threonine-protein kinase PLK1 7
- Serine/threonine-protein kinase PLK2 7
- Insulin receptor-related protein 7
- Inhibitor of nuclear factor kappa-B kinase subunit beta 7
- Serine/threonine-protein kinase NIM1 7
- Serine/threonine-protein kinase PLK3 7
- Serine/threonine-protein kinase PLK4 7
- Tyrosine-protein kinase receptor TYRO3 7
- Wee1-like protein kinase 2 7
- Serine/threonine-protein kinase BRSK1 7
- Serine/threonine-protein kinase LATS2 7
- Citron Rho-interacting kinase 7
- Platelet-derived growth factor receptor alpha 7
- Serine/threonine-protein kinase BRSK2 7
- Serine/threonine-protein kinase Chk2 7
- Serine/threonine-protein kinase Chk1 7
- cAMP-dependent protein kinase catalytic subunit PRKX 7
- SRSF protein kinase 1 7
- Tyrosine-protein kinase Yes 7
- Serine/threonine-protein kinase MRCK beta 7
- Serine/threonine-protein kinase MRCK gamma 7
- Casein kinase II subunit alpha' 7
- Dual specificity tyrosine-phosphorylation-regulated kinase 2 7
- Serine/threonine-protein kinase STK11 7
- Cyclin-G-associated kinase 7
- Receptor tyrosine-protein kinase erbB-4 7
- Receptor tyrosine-protein kinase erbB-2 7
- Tyrosine-protein kinase FRK 7
- Receptor tyrosine-protein kinase erbB-3 7
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 7
- Hepatocyte growth factor receptor 7
- Serine/threonine-protein kinase B-raf 7
- Serine/threonine-protein kinase Nek9 7
- Serine/threonine-protein kinase Nek7 7
- Glycogen synthase kinase-3 alpha 7
- Serine/threonine-protein kinase Nek6 7
- Serine/threonine-protein kinase Nek5 7
- Serine/threonine-protein kinase Nek2 7
- Serine/threonine-protein kinase receptor R3 7
- Serine/threonine-protein kinase Nek1 7
- Macrophage-stimulating protein receptor 7
- Cyclin-dependent kinase-like 3 7
- Serine/threonine-protein kinase SIK3 [59-1321] 7
- Cyclin-dependent kinase-like 2 7
- MAP/microtubule affinity-regulating kinase 3 7
- Homeodomain-interacting protein kinase 4 7
- Homeodomain-interacting protein kinase 3 7
- MAP kinase-interacting serine/threonine-protein kinase 2 7
- MAP kinase-interacting serine/threonine-protein kinase 1 7
- Cyclin-dependent kinase-like 5 7
- Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 7
- Serine/threonine-protein kinase 10 7
- MAP/microtubule affinity-regulating kinase 4 7
- Proto-oncogene tyrosine-protein kinase receptor Ret 7
- Serine/threonine-protein kinase 38-like 7
- Dual specificity protein kinase TTK 7
- Myosin-IIIb 7
- Myosin-IIIa 7
- Tyrosine-protein kinase ITK/TSK 7
- Myotonin-protein kinase 7
- Protein kinase C eta type 7
- Bone morphogenetic protein receptor type-1B 7
- Bone morphogenetic protein receptor type-1A 7
- Tyrosine-protein kinase Blk 7
- Receptor-interacting serine/threonine-protein kinase 1 7
- Serine/threonine-protein kinase 16 7
- Receptor-interacting serine/threonine-protein kinase 2 7
- Epidermal growth factor receptor 7
- Non-receptor tyrosine-protein kinase TNK1 7
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 7
- Serine/threonine-protein kinase NLK 7
- Homeodomain-interacting protein kinase 2 7
- Homeodomain-interacting protein kinase 1 7
- Receptor-interacting serine/threonine-protein kinase 4 7
- Ribosomal protein S6 kinase beta-1 7
- Serine/threonine-protein kinase OSR1 7
- Casein kinase I isoform delta 7
- Cyclin-dependent kinase 18 [3-474] 7
- RAF proto-oncogene serine/threonine-protein kinase 7
- Serine/threonine-protein kinase 26 7
- Serine/threonine-protein kinase 24 7
- Serine/threonine-protein kinase 25 7
- Dual specificity testis-specific protein kinase 1 7
- Ephrin type-B receptor 3 7
- Serine/threonine-protein kinase 33 7
- Ephrin type-B receptor 4 7
- Ephrin type-B receptor 1 7
- Ephrin type-B receptor 2 7
- MAP kinase-activated protein kinase 2 7
- Ephrin type-B receptor 6 7
- Platelet-derived growth factor receptor beta 7
- Epithelial discoidin domain-containing receptor 1 7
- MAP kinase-activated protein kinase 5 7
- STE20/SPS1-related proline-alanine-rich protein kinase 7
- Muscle, skeletal receptor tyrosine-protein kinase 7
- Tyrosine-protein kinase Fer 7
- Tyrosine-protein kinase receptor Tie-1 7
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 7
- Calcium/calmodulin-dependent protein kinase type II subunit delta 7
- Proto-oncogene tyrosine-protein kinase ROS 7
- Serine/threonine-protein kinase DCLK1 7
- Calcium/calmodulin-dependent protein kinase kinase 1 7
- Serine/threonine-protein kinase DCLK2 7
- Serine/threonine-protein kinase TAO3 7
- Calcium/calmodulin-dependent protein kinase kinase 2 7
- Serine/threonine-protein kinase DCLK3 7
- Serine/threonine-protein kinase TNNI3K 7
- Interferon-induced, double-stranded RNA-activated protein kinase 7
- Angiopoietin-1 receptor 7
- Mitogen-activated protein kinase kinase kinase kinase 2 7
- Mitogen-activated protein kinase kinase kinase kinase 3 7
- Mast/stem cell growth factor receptor Kit 7
- Mitogen-activated protein kinase kinase kinase kinase 1 7
- Serine/threonine-protein kinase MRCK alpha 7
- Mitogen-activated protein kinase kinase kinase kinase 4 7
- Mitogen-activated protein kinase kinase kinase kinase 5 7
- Mitogen-activated protein kinase 15 7
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 7
- Activin receptor type-1B 7
- Myosin light chain kinase family member 4 7
- Mitogen-activated protein kinase kinase kinase 9 7
- Mitogen-activated protein kinase kinase kinase 6 7
- RAC-gamma serine/threonine-protein kinase 7
- Mitogen-activated protein kinase kinase kinase 5 7
- Interleukin-1 receptor-associated kinase 1 7
- Mitogen-activated protein kinase kinase kinase 7 7
- Interleukin-1 receptor-associated kinase 3 7
- Mitogen-activated protein kinase kinase kinase 2 7
- Mitogen-activated protein kinase kinase kinase 1 7
- Mitogen-activated protein kinase kinase kinase 4 7
- Mitogen-activated protein kinase kinase kinase 3 7
- Serine/threonine-protein kinase ICK 7
- RAC-alpha serine/threonine-protein kinase 7
- Megakaryocyte-associated tyrosine-protein kinase 7
- Proto-oncogene tyrosine-protein kinase Src 7
- Activin receptor type-2B 7
- Activin receptor type-2A 7
- BDNF/NT-3 growth factors receptor 7
- Serine/threonine-protein kinase 17A 7
- Tyrosine-protein kinase Lck 7
- Serine/threonine-protein kinase 17B 7
- Mitogen-activated protein kinase kinase kinase 19 7
- Dual specificity protein kinase CLK1 7
- Protein kinase C delta type 7
- Mitogen-activated protein kinase kinase kinase 15 7
- NT-3 growth factor receptor 7
- G protein-coupled receptor kinase 4 7
- Dual specificity protein kinase CLK4 7
- Dual specificity protein kinase CLK3 7
- Dual specificity protein kinase CLK2 7
- High affinity nerve growth factor receptor 7
- Protein-tyrosine kinase 2-beta 7
- Tyrosine-protein kinase Mer 7
- Poly [ADP-ribose] polymerase tankyrase-2 7
- Serine/threonine-protein kinase N2 7
- cAMP-dependent protein kinase catalytic subunit beta 7
- Serine/threonine-protein kinase N1 7
- Ribosomal protein S6 kinase alpha-3 7
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 7
- Calcium/calmodulin-dependent protein kinase type 1D 7
- STE20-like serine/threonine-protein kinase 7
- Hormonally up-regulated neu tumor-associated kinase 7
- Fibroblast growth factor receptor 4 7
- Tyrosine-protein kinase Fgr 7
- Aurora kinase B 7
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 7
- Aurora kinase A 7
- Mitogen-activated protein kinase kinase kinase 20 7
- Fibroblast growth factor receptor 1 7
- Fibroblast growth factor receptor 2 7
- Atypical kinase COQ8A, mitochondrial 7
- Fibroblast growth factor receptor 3 7
- Aurora kinase C 7
- Mitogen-activated protein kinase 13 7
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 7
- Mitogen-activated protein kinase 12 7
- Mitogen-activated protein kinase 11 7
- Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 7
- RAC-beta serine/threonine-protein kinase 7
- Mitogen-activated protein kinase 10 7
- Casein kinase I isoform alpha 7
- Misshapen-like kinase 1 7
- Tyrosine-protein kinase Fyn 7
- Tyrosine-protein kinase CSK 7
- Macrophage colony-stimulating factor 1 receptor 7
- Protein kinase C alpha type 7
- Maternal embryonic leucine zipper kinase 7
- Serine/threonine-protein kinase MARK1 7
- Serine/threonine-protein kinase MARK2 7
- TRAF2 and NCK-interacting protein kinase 7
- Mitogen-activated protein kinase kinase kinase 13 7
- Mitogen-activated protein kinase kinase kinase 10 7
- Mitogen-activated protein kinase kinase kinase 11 7
Publications 1 ▿
- Blood 114: 2984-92 (2009) 2521
Institutions 1 ▿
- [Ambit Biosciences] 2521
Affinity: 0.075 to 7.5E+5 nM▿
- IC50 8
- Kd 2513
- Affinity ≤ nM
Xtal structures: 4
Docked structures: 5
Catalog Cmpds: 7