Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304608(5,5'-(propane-1,3-diyl)bis(1,3,4-oxadiazole-2(3H)-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304607(5-(3-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304609(5-[4-t-Butyldimethylsilyloxy phenyl]-1,3,4-oxadiaz...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304605(5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione...)copy SMILEScopy InChI
Affinity DataKi:  8.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304606(5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)copy SMILEScopy InChI
Affinity DataKi:  8.50E+5nMAssay Description:Noncompetitive inhibition of human recombinant NPP1 by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304609(5-[4-t-Butyldimethylsilyloxy phenyl]-1,3,4-oxadiaz...)copy SMILEScopy InChI
Affinity DataIC50: 3.68E+5nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304608(5,5'-(propane-1,3-diyl)bis(1,3,4-oxadiazole-2(3H)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.67E+5nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304607(5-(3-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)copy SMILEScopy InChI
Affinity DataIC50: 4.94E+5nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304606(5-(4-(benzyloxy)phenyl)-1,3,4-oxadiazole-2(3H)-thi...)copy SMILEScopy InChI
Affinity DataIC50: 6.28E+5nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304605(5-(4-hydroxyphenyl)-1,3,4-thiadiazole-2(3H)-thione...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304604(5-(pyridin-4-yl)-1,3,4-thiadiazole-2(3H)-thione | ...)copy SMILEScopy InChI
Affinity DataIC50: 9.98E+5nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304602(5-(4-(tert-butyldimethylsilyloxy)phenyl)-1,3,4-thi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
University of Karachi

Curated by ChEMBL
LigandPNGBDBM50304603(5,5'-methylenebis(1,3,4-oxadiazole-2(3H)-thione) |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant NPP1 assessed as release of p-nitrophenol by microtitre plate spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82X2PubMed
* indicates data uncertainty>20%