Compile Data Set for Download or QSAR

Found 6 hits of Enzyme Inhibition Constant Data   

TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308672(CHEMBL590070 | N-(Propylamide-benzophenone)-1-deox...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of 4-methylumbelliferyl from non-lysosomal GBA2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82ZHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308673(CHEMBL589341 | N-(Propylamide-acetophenone)-1-deox...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Displacement of 4-methylumbelliferyl from non-lysosomal GBA2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82ZHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308672(CHEMBL590070 | N-(Propylamide-benzophenone)-1-deox...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of 4-methylumbelliferyl from human GBA by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82ZHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50308673(CHEMBL589341 | N-(Propylamide-acetophenone)-1-deox...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Displacement of 4-methylumbelliferyl from human GBA by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82ZHPubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 2.88E+4nMAssay Description:Displacement of 4-methylumbelliferyl from non-lysosomal GBA2 by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82ZHPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 5.06E+5nMAssay Description:Displacement of 4-methylumbelliferyl from human GBA by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC82ZHPubMed
* indicates data uncertainty>20%