Compile Data Set for Download or QSAR

Found 24 hits of Enzyme Inhibition Constant Data   

TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303940(2-(Benzylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303950(CHEMBL583687 | Isosorbide-2-benzylcarbamate-5-(o-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253231((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303952(2-(Dimethylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303951(2-(Ethylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 9.60nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253266((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303941(2-(Benzylaminocarbonyloxy-)5-O-(m-hydroxybenzoyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303943(2-(Benzylaminocarbonyloxy-)5-O-(o-nitro-benzoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303946(2-(benzylaminocarbonyloxy-)5-O-(o-amino-benzoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303944(2-(Benzylaminocarbonyloxy-)5-O-(m-nitro-benzoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of BuChEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMedDrugBank
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303949(2-(Benzylaminocarbonyloxy-)5-O-(o-nitroso-benzoyl)...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of electric eel AChE type 6SMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253230((3R,3aR,6S,6aR)-6-(benzylcarbamoyloxy)hexahydrofur...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303939((3R,3aR,6S,6aR)-6-(butylcarbamoyloxy)hexahydrofuro...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303947(2-(Benzylaminocarbonyloxy-)5-O-(m-amino-benzoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303945(2-(Benzylaminocarbonyloxy-)5-O-(p-nitro-benzoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303948(2-(Benzylaminocarbonyloxy-)5-O-(p-amino-benzoyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 297nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303942(2-(Benzylaminocarbonyloxy-)5-O-(p-hydroxy-benzoyl)...)copy SMILEScopy InChI
Affinity DataIC50: 323nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303954(2-(Morpholinocarbonyloxy-)5-O-salicyloyl-1,4:3,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303953(2-(Diethylaminocarbonyloxy-)5-O-salicyloyl-1,4:3,6...)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCocaine esterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50303940(2-(Benzylaminocarbonyloxy-)5-O-Salicyloyl-1,4:3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of human CES2-mediated pNPA substrate turnoverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50252790(CHEMBL524046 | Isosorbide-2-benzylcarbamate | isos...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of BuChE in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M37S1PubMed
* indicates data uncertainty>20%