Compile Data Set for Download or QSAR

Found 28 hits of Enzyme Inhibition Constant Data   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)copy SMILEScopy InChI
Affinity DataKi:  0.150nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi:  0.190nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307102(7-oxo-1-(3-(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-y...)copy SMILEScopy InChI
Affinity DataKi:  0.25nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307100(1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHEN...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307093(CHEMBL591955 | N-(3-fluoro-2'-(methylsulfonyl)biph...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307099((R)-6-(2'-((3-hydroxypyrrolidin-1-yl)methyl)biphen...)copy SMILEScopy InChI
Affinity DataKi:  0.840nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307098(6-(2'-((dimethylamino)methyl)biphenyl-4-yl)-1-(3-(...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307097(6-(4-(2-((dimethylamino)methyl)-1H-imidazol-1-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307096(6-(2'-(METHYLSULFONYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4...)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307101(3-METHYL-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-...)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307092(1-(3-((2-aminoacetamido)methyl)phenyl)-N-(3-fluoro...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307095(1-(3-(5-amino-4H-1,2,4-triazol-3-yl)phenyl)-N-(3-f...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307094(1-(3-(5-amino-1,3,4-thiadiazol-2-yl)phenyl)-N-(3-f...)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307095(1-(3-(5-amino-4H-1,2,4-triazol-3-yl)phenyl)-N-(3-f...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307099((R)-6-(2'-((3-hydroxypyrrolidin-1-yl)methyl)biphen...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307102(7-oxo-1-(3-(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-y...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307096(6-(2'-(METHYLSULFONYL)BIPHENYL-4-YL)-1-(3-(5-OXO-4...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307101(3-METHYL-1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307098(6-(2'-((dimethylamino)methyl)biphenyl-4-yl)-1-(3-(...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307100(1-(3-(5-OXO-4,5-DIHYDRO-1H-1,2,4-TRIAZOL-3-YL)PHEN...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM12657(1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsul...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307097(6-(4-(2-((dimethylamino)methyl)-1H-imidazol-1-yl)p...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307092(1-(3-((2-aminoacetamido)methyl)phenyl)-N-(3-fluoro...)copy SMILEScopy InChI
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307093(CHEMBL591955 | N-(3-fluoro-2'-(methylsulfonyl)biph...)copy SMILEScopy InChI
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50307094(1-(3-(5-amino-1,3,4-thiadiazol-2-yl)phenyl)-N-(3-f...)copy SMILEScopy InChI
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
* indicates data uncertainty>20%