Compile Data Set for Download or QSAR

Found 15 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313879((5S)-5-butyl-9-((3aR,6aS)-2-(4,6-dimethylpyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313880(5-((3aR,6aS)-5-((S)-5-butyl-2-oxo-3-((tetrahydro-2...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313885(CHEMBL1077364 | trans-(5S)-5-butyl-9-((3aR,6aS)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313881((5S)-5-butyl-9-((3aR,6aS)-2-(4,6-dimethylpyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313886(CHEMBL1077365 | trans-(5S)-5-butyl-3-((4-cycloprop...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313884(CHEMBL1077363 | trans-(5S)-5-butyl-9-((3aR,6aS)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313883(CHEMBL1077362 | trans-(5S)-5-butyl-9-((3aR,6aS)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313878(5-((3aR,6aS)-5-((S)-4-((1S,2S)-2-ethoxy-5-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313882(5-((3aR,6aS)-5-((S)-5-butyl-2-oxo-3-((tetrahydro-2...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313876((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-((S)-4-((...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313877((2,4-dimethylpyridin-3-yl)((3aR,6aS)-5-((S)-4-((1S...)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313873((4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-((S)-4-((...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313875(5-((3aR,6aS)-5-((S)-4-((R)-2-methoxy-1-(4-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313874((2,4-dimethylpyridin-3-yl)((3aR,6aS)-5-((S)-4-((R)...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W7TPubMed
* indicates data uncertainty>20%