Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

TargetP2Y purinoceptor 12(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318031(CHEMBL1097279 | cangrelor)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at P2Y12 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318031(CHEMBL1097279 | cangrelor)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318030(((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-(methylamino)-9H...)copy SMILEScopy InChI
Affinity DataIC50: 112nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318029(CHEMBL1096400 | diammonium (2R,3S,5R)-2-[(hydrogen...)copy SMILEScopy InChI
Affinity DataIC50: 508nMAssay Description:Antagonist activity at P2Y1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318029(CHEMBL1096400 | diammonium (2R,3S,5R)-2-[(hydrogen...)copy SMILEScopy InChI
Affinity DataIC50: 508nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318028(CHEMBL1094760 | diammonium (2R,3S,5R)-5-(6-amino-2...)copy SMILEScopy InChI
Affinity DataIC50: 582nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318026(((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-...)copy SMILEScopy InChI
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318022(CHEMBL1096401 | uridine diphosphate trisodium salt)copy SMILEScopy InChI
Affinity DataEC50:  1.14E+3nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318027(((2R,3S,4R,5R)-5-(6-amino-2-(phenylethynyl)-9H-pur...)copy SMILEScopy InChI
Affinity DataEC50:  0.0360nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318025(((2R,3S,4R,5R)-5-(6-chloro-4-(methylamino)-1H-imid...)copy SMILEScopy InChI
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50306710(((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...)copy SMILEScopy InChI
Affinity DataEC50:  945nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50318024(((2R,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-puri...)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
* indicates data uncertainty>20%