Compile Data Set for Download or QSAR

Found 33 hits of Enzyme Inhibition Constant Data   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321683(4-chlorobenzyl allyl(1-(((3S,4R)-1-(cyclopentaneca...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321697(1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321712(CHEMBL1172625 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321699(1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321700(1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321694(1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321711(CHEMBL1172624 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321695(1-allyl-3-(4-chlorobenzyl)-1-(1-(((3S,4R)-1-(cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321682(CHEMBL1172035 | nifeviroc)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321701(4-((3-allyl-3-(1-(((3S,4R)-1-(cyclopentanecarbonyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321696(1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321713(CHEMBL1172626 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321682(CHEMBL1172035 | nifeviroc)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced calcium elevationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321703(CHEMBL1172157 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321707(CHEMBL1171030 | N-allyl-2-(4-chlorophenyl)-N-(1-((...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321710(CHEMBL1172623 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321702(4-((3-allyl-3-(1-(((3S,4R)-1-(cyclopentanecarbonyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321705(CHEMBL1172439 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321691(4-methoxybenzyl allyl(1-(((3S,4R)-1-(cyclopentanec...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321698(1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321685(4-(trifluoromethoxy)benzyl allyl(1-(((3S,4R)-1-(cy...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321692(CHEMBL1171965 | benzyl allyl(1-(((3S,4R)-1-(cyclop...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321706(CHEMBL1171029 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321704(CHEMBL1172438 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321708(CHEMBL1169819 | N-allyl-2-(4-bromophenyl)-N-(1-(((...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321688(4-bromobenzyl allyl(1-(((3S,4R)-1-(cyclopentanecar...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321689(4-(trifluoromethyl)benzyl allyl(1-(((3S,4R)-1-(cyc...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321686(4-(methylsulfonyl)benzyl allyl(1-(((3S,4R)-1-(cycl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321693(1-allyl-3-benzyl-1-(1-(((3S,4R)-1-(cyclopentanecar...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321687(CHEMBL1172041 | benzo[c][1,2,5]oxadiazol-5-ylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321690(CHEMBL1172037 | benzo[d][1,3]dioxol-5-ylmethyl all...)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321709(CHEMBL1172622 | N-allyl-N-(1-(((3S,4R)-1-(cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50321684(4-fluorobenzyl allyl(1-(((3S,4R)-1-(cyclopentaneca...)copy SMILEScopy InChI
Affinity DataIC50: 221nMAssay Description:Antagonist activity at CCR5 expressed in CHO cells assessed as inhibition of RANTES-induced [35S]GTPgamma binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H132Z4PubMed
* indicates data uncertainty>20%