Compile Data Set for Download or QSAR

Found 39 hits of Enzyme Inhibition Constant Data   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074789(3-Amino-2-phenyl-quinoline-4-carboxylic acid ((R)-...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50051293((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50412944(CHEMBL479652)copy SMILEScopy InChI
Affinity DataKi:  3.16nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50412945(CHEMBL516441)copy SMILEScopy InChI
Affinity DataKi:  3.98nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50412947(5-(3-METHYL-1-TRIAZENO)IMIDAZOLE-4-CARBOXAMIDE)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50412946(CHEMBL517691)copy SMILEScopy InChI
Affinity DataKi:  5.01nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50412949(CHEMBL519790)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074774(3-Methoxy-2-phenyl-quinoline-4-carboxylic acid ((R...)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074776(3-Ethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-...)copy SMILEScopy InChI
Affinity DataKi:  6.31nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50412950(CHEMBL479450)copy SMILEScopy InChI
Affinity DataKi:  7.94nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50412938(CHEMBL520086)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50051295((S)-3-methyl-2-phenyl-N-(1-phenylpropyl)quinoline-...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074792(2-Phenyl-3-propyl-quinoline-4-carboxylic acid (1-p...)copy SMILEScopy InChI
Affinity DataKi:  12.6nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074802(3-Butyl-2-phenyl-quinoline-4-carboxylic acid (1-ph...)copy SMILEScopy InChI
Affinity DataKi:  15.8nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074806(2-Phenyl-quinoline-4-carboxylic acid (2-oxo-1-phen...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50051294(2-Phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  31.6nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50051289((R)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]...)copy SMILEScopy InChI
Affinity DataKi:  31.6nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074788(2,3-Diphenyl-quinoline-4-carboxylic acid (1-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074824(3-Hexyl-2-phenyl-quinoline-4-carboxylic acid (1-ph...)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074797(2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-but...)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074780(2-Phenyl-quinoline-4-carboxylic acid (2-methyl-1-p...)copy SMILEScopy InChI
Affinity DataKi:  79.4nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50417383(CHEMBL1277075)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074786(2-Phenyl-quinoline-4-carboxylic acid (2-hydroxy-1-...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074783(2-Phenyl-quinoline-4-carboxylic acid (3-hydroxy-1-...)copy SMILEScopy InChI
Affinity DataKi:  398nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074778(2-Phenyl-quinoline-4-carboxylic acid (methylcarbam...)copy SMILEScopy InChI
Affinity DataKi:  501nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074808(2-Phenyl-quinoline-4-carboxylic acid (2,2,2-triflu...)copy SMILEScopy InChI
Affinity DataKi:  501nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074807(2-Phenyl-quinoline-4-carboxylic acid (dimethylcarb...)copy SMILEScopy InChI
Affinity DataKi:  501nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074820(2-Phenyl-quinoline-4-carboxylic acid (carbamoyl-ph...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074801(3-Phenyl-3-[(2-phenyl-quinoline-4-carbonyl)-amino]...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074803(2-Phenyl-quinoline-4-carboxylic acid (1,2-diphenyl...)copy SMILEScopy InChI
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074821(2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-oct...)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50331034(2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-car...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50051293((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity against human NK3 receptor expressed in HEK293 cells assessed as inhibition of increase of intracellular calcium level by fluores...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50051293((S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinol...)copy SMILEScopy InChI
Affinity DataIC50: 16.6nMAssay Description:Antagonist activity against human NK3 receptor expressed in HEK293 cells assessed as inhibition of NKB-induced increase of intracellular calcium leve...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074822(2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-eth...)copy SMILEScopy InChI
Affinity DataIC50: 33.5nMAssay Description:Displacement of [125I]-MePhe7-NKB from human NK3 receptor expressed in CHO cells after 90 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50331034(2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-car...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Antagonist activity against human NK3 receptor expressed in CHO cells assessed as inhibition of senktide-induced increase of intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50331034(2-phenyl-N-(1-(pyridin-2-yl)propyl)quinoline-4-car...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity against human NK3 receptor expressed in HEK293 cells assessed as inhibition of MePhe7-NKB-induced increase of intracellular calci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074822(2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-eth...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity against human NK3 receptor expressed in CHO cells assessed as inhibition of senktide-induced increase of intracellular calcium le...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50074822(2-Phenyl-quinoline-4-carboxylic acid (1-phenyl-eth...)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:Antagonist activity against human NK3 receptor expressed in HEK293 cells assessed as inhibition of MePhe7-NKB-induced increase of intracellular calci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736R5FPubMed
* indicates data uncertainty>20%