Found 44 hits of Enzyme Inhibition Constant Data
Affinity DataKi: 2.51nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
Affinity DataKi: 34.7nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
Affinity DataKi: 37.1nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD
Curated by ChEMBL
MSD
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-dofetilide from human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 31.6nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38.9nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 47.9nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57.5nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61.7nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 72.4nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit PRKX(Homo sapiens (Human))
MSD
Curated by ChEMBL
MSD
Curated by ChEMBL
Affinity DataIC50: 79.4nMAssay Description:Inhibition of human PrkX by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79.4nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81.3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 91.2nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 229nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of ROCK1 by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of human PKCdelta by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of human PKCeta by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 501nMAssay Description:Inhibition of human PKCmu by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 525nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 575nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 589nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 661nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
Affinity DataIC50: 676nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 759nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 776nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
Affinity DataIC50: 871nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of ROCK1 by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit PRKX(Homo sapiens (Human))
MSD
Curated by ChEMBL
MSD
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human PrkX by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCmu by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PKCeta by RFBA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human PKCdelta by RFBA assayMore data for this Ligand-Target Pair
