Compile Data Set for Download or QSAR

Found 22 hits of Enzyme Inhibition Constant Data   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM6471(4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM8((1R)-cyclohexane-1,2-diol | cis-1,2-cyclohexanedio...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMedDrugBank
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM12255(AZD0530 | CHEMBL217092 | Compound 33 | N-(5-chloro...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50303801(CHEMBL571546 | N-benzyl-2-(5-(4-(2-morpholinoethox...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342390(3-Amino-6-(2-dimethylamino-ethylamino)-4-phenylthi...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342392(3-Amino-4-benzyl-6-(2-dimethylamino-ethylamino)-th...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342393(3-Amino-6-(2-dimethylamino-ethylamino)-4-propylthi...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342391(3-Amino-6-(2-dimethylamino-ethylamino)-4-phenylthi...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342389(3-Amino-6-(2-dimethylamino-ethylamino)-4-phenylthi...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342387(3-Amino-6-(2-dimethylamino-ethylamino)-4-methylthi...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342388(3-Amino-6-(2-dimethylamino-ethylamino)-4-methylthi...)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342379(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 269nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342386(3-Amino-4-methyl-6-trifluoromethyl-thieno[2,3-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342381(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 769nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342384(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342382(3-Amino-thieno[2,3-b]pyridine-2-carboxylic acid(3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342385(3-Amino-4-methyl-6-trifluoromethyl-thieno[2,3-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342395(3-Amino-6-(2-dimethylamino-ethylamino)-5-propylthi...)copy SMILEScopy InChI
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342394(3-Amino-5-benzyl-6-(2-dimethylamino-ethylamino)-th...)copy SMILEScopy InChI
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342383(3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut de Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50342380(3-Amino-thieno[2,3-b]pyridine-2-carboxylic acid na...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN45CDPubMed
* indicates data uncertainty>20%