Compile Data Set for Download or QSAR

Found 28 hits of Enzyme Inhibition Constant Data   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346528(2,5-dihydro-1H-pyrrole-2-carboximidamide | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346520(CHEMBL1783072 | cyclobutanecarboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346527(CHEMBL1783092 | pyrrolidine-2-carboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346519(CHEMBL1783071 | cyclopropanecarboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346529((R)-azetidine-2-carboximidamide | CHEMBL1783094 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346521(CHEMBL1229853 | cyclopentanecarboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346526(CHEMBL1783091 | tetrahydrothiophene-2-carboximidam...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346525(CHEMBL1783090 | tetrahydrofuran-2-carboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346531(CHEMBL1783096 | azetidine-3-carboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346523(CHEMBL1783074 | piperidine-3-carboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346524(CHEMBL1783089 | piperidine-4-carboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346522(CHEMBL1783073 | piperidine-2-carboximidamide)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant iNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human recombinant nNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50086467((S)-4-(2-Acetimidoylamino-ethylsulfanyl)-2-amino-b...)copy SMILEScopy InChI
Affinity DataIC50: 4.66E+5nMAssay Description:Inhibition of human recombinant eNOS by microtiter plate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346532((R)-pyrrolidine-2-carboximidamide | CHEMBL1783097)copy SMILEScopy InChI
Affinity DataKd:  630nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50346533((S)-pyrrolidine-2-carboximidamide | CHEMBL1783098)copy SMILEScopy InChI
Affinity DataKd: >4.00E+4nMAssay Description:Binding affinity to human recombinant iNOS delta 65 residueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB538TPubMed
* indicates data uncertainty>20%