Compile Data Set for Download or QSAR

Found 31 hits of Enzyme Inhibition Constant Data   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM20732((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345159(CHEMBL1779539)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345167(CHEMBL1779547)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50344140(CHEMBL1778208)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345150((3aR)-13,13,16-trimethyl-15-oxo-1,2,3,3a,4,5,12,14...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345153(CHEMBL1779533)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345155(CHEMBL1779535)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340250((6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345152(CHEMBL1779532)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345158(CHEMBL1779538)copy SMILEScopy InChI
Affinity DataIC50: 153nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345165(CHEMBL1779545)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345164(CHEMBL1779544)copy SMILEScopy InChI
Affinity DataIC50: 188nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345156(CHEMBL1779536)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345163(CHEMBL1779543)copy SMILEScopy InChI
Affinity DataIC50: 301nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345156(CHEMBL1779536)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345161(CHEMBL1779541)copy SMILEScopy InChI
Affinity DataIC50: 496nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345160(CHEMBL1779540)copy SMILEScopy InChI
Affinity DataIC50: 634nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345162(CHEMBL1779542)copy SMILEScopy InChI
Affinity DataIC50: 883nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345152(CHEMBL1779532)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345166(CHEMBL1779546)copy SMILEScopy InChI
Affinity DataIC50: 982nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345151(CHEMBL1779531)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345165(CHEMBL1779545)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345150((3aR)-13,13,16-trimethyl-15-oxo-1,2,3,3a,4,5,12,14...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345154(CHEMBL1779534)copy SMILEScopy InChI
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345167(CHEMBL1779547)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345157(CHEMBL1779537)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345153(CHEMBL1779533)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345159(CHEMBL1779539)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345150((3aR)-13,13,16-trimethyl-15-oxo-1,2,3,3a,4,5,12,14...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345155(CHEMBL1779535)copy SMILEScopy InChI
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of human ERG by HT patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50345150((3aR)-13,13,16-trimethyl-15-oxo-1,2,3,3a,4,5,12,14...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SRC-related membrane-associated tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GVPPubMed
* indicates data uncertainty>20%