Compile Data Set for Download or QSAR

Found 51 hits of Enzyme Inhibition Constant Data   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50314073(3-(3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-ox...)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346920(CHEMBL1795686)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346919(CHEMBL1795685)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50314073(3-(3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-ox...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataKi:  193nMAssay Description:Inhibition of p38alpha kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50314073(3-(3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-ox...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50314073(3-(3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346924(CHEMBL1795684)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346920(CHEMBL1795686)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346923(CHEMBL1795683)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50314073(3-(3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of p38alpha kinase in human monocytesMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of p38alpha kinase in human monocytesMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346922(CHEMBL1795682)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346921(CHEMBL1795681)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346919(CHEMBL1795685)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346925(CHEMBL1795687)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346926(CHEMBL1795688)copy SMILEScopy InChI
Affinity DataIC50: 193nMAssay Description:Inhibition of p38alpha kinase-dependent HSP-27 phosphorylation in human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 249nMAssay Description:Inhibition of p38beta kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TBK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MST2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKK betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetDual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MKK6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ZAP70More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MKK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMAP kinase-activated protein kinase 3(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MYT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetAurora kinase A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AURKAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MKK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CHK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346918(CHEMBL1738710)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346920(CHEMBL1795686)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73F2SPubMed
Displayed 1 to 50 (of 51 total ) | Next | Last >>* indicates data uncertainty>20%