Compile Data Set for Download or QSAR

Found 115 hits of Enzyme Inhibition Constant Data   

TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352418(CHEMBL1823863)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352419(CHEMBL1823864)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352296(CHEMBL1822468)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352419(CHEMBL1823864)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352418(CHEMBL1823863)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352296(CHEMBL1822468)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352420(CHEMBL1823865)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352433(CHEMBL1823821)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352424(CHEMBL1823579)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352420(CHEMBL1823865)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352435(CHEMBL1823825)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352396(CHEMBL1823841)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352397(CHEMBL1823842)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352400(CHEMBL1823845)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352439(CHEMBL1823831)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352416(CHEMBL1823861)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352440(CHEMBL1823832)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352423(CHEMBL1823584)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352395(CHEMBL1823840)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352477(CHEMBL1823830)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352415(CHEMBL1823860)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352475(CHEMBL1823824)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352441(CHEMBL1823833)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352437(CHEMBL1823828)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352428(CHEMBL1823587)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352427(CHEMBL1823586)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352438(CHEMBL1823829)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352417(CHEMBL1823862)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352421(CHEMBL1823591)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352457(CHEMBL1823602)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352394(CHEMBL1823839)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352417(CHEMBL1823862)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352426(CHEMBL1823585)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352414(CHEMBL1823859)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352431(CHEMBL1823590)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352422(CHEMBL1823616)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352432(CHEMBL1823617)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352444(CHEMBL1823836)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352416(CHEMBL1823861)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352467(CHEMBL1823612)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352399(CHEMBL1823844)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352442(CHEMBL1823834)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352412(CHEMBL1823857)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352436(CHEMBL1823827)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352446(CHEMBL1823838)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352415(CHEMBL1823860)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352398(CHEMBL1823843)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352443(CHEMBL1823835)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
TargetSmoothened homolog(Homo sapiens (Human))
Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50352414(CHEMBL1823859)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90DSPubMed
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