Compile Data Set for Download or QSAR

Found 13 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50354745(CHEMBL1834084)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)copy SMILEScopy InChI
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM32546(arylsulfonylpiperazine, 18)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM32547(arylsulfonylpiperazine, 19)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50117901(2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 28.4nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50354740(CHEMBL1834080)copy SMILEScopy InChI
Affinity DataIC50: 28.8nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50354741(CHEMBL1834081)copy SMILEScopy InChI
Affinity DataIC50: 32.7nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50354746(CHEMBL1834085)copy SMILEScopy InChI
Affinity DataIC50: 41.3nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50354742(CHEMBL1834082)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM72094(1-(2,3-Dihydro-indol-1-yl)-2-(5,6-diphenyl-[1,2,4]...)copy SMILEScopy InChI
Affinity DataIC50: 58.1nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50354743(CHEMBL1834083)copy SMILEScopy InChI
Affinity DataIC50: 66.7nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50354744(CHEMBL1379780)copy SMILEScopy InChI
Affinity DataIC50: 102nMAssay Description:Inhibition of human 11beta HSD1 expressed in HEK293 cells assessed as assessed as inhibition of [1,2-(n)3H]cortisone to [3H]-cortisol after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Shanghai Pharmaceutical Holding Co. Ltd

Curated by ChEMBL
LigandPNGBDBM72094(1-(2,3-Dihydro-indol-1-yl)-2-(5,6-diphenyl-[1,2,4]...)copy SMILEScopy InChI
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1K0CPubMed
* indicates data uncertainty>20%