Compile Data Set for Download or QSAR

Found 18 hits of Enzyme Inhibition Constant Data   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356471(CHEMBL1911861)copy SMILEScopy InChI
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356467(CHEMBL1911855)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356469(CHEMBL1911857)copy SMILEScopy InChI
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356468(CHEMBL1911856)copy SMILEScopy InChI
Affinity DataKi:  77nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356466(CHEMBL1911854)copy SMILEScopy InChI
Affinity DataKi:  87nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356465(CHEMBL1911853)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356472(CHEMBL1911862)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356464(CHEMBL1911852)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356470(CHEMBL1911858)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356473(CHEMBL1911864)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataKi:  420nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataKd:  0.400nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50320567(3-(2,4-Dihydroxybenzylidene)anabaseine | CHEMBL116...)copy SMILEScopy InChI
Affinity DataKd:  0.800nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50356472(CHEMBL1911862)copy SMILEScopy InChI
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat recombinant alpha7 nAChR expressed in GH4C1 cells by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50061564((3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-...)copy SMILEScopy InChI
Affinity DataKd:  19nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50264117(3-[1-(4-Hydroxy-2-methoxy-phenyl)-meth-(E)-ylidene...)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at rat recombinant alpha7 nAChR expressed in GH4C1 cells by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
Targacept Inc

Curated by ChEMBL
LigandPNGBDBM50320526(3-(4-Aminobenzylidene)anabaseine | CHEMBL1163383)copy SMILEScopy InChI
Affinity DataKd:  0.800nMAssay Description:Displacement of [3H]-epibatidine from Lymnaea stagnalis N-terminal FLAG-tagged AChBP expressed in HEK293 cells after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q4DPubMed
* indicates data uncertainty>20%