Found 48 hits of Enzyme Inhibition Constant Data
Affinity DataKi: 500nMAssay Description:Inhibition of adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Inhibition of muscarinic M4 receptorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human VEGFR1 using ATP as substrateMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human TRK-A using ATP as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human TRK-B using ATP as substrateMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human RET using ATP as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse BLK using ATP as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human FGFR1 using ATP as substrateMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human TAK1 using ATP as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human MST2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human cSrc using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human Aurora-A using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of CK1 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human Tie2 expressed in porcine PAE145 cells cotransfected with chimeric rat TRK-A/KDR receptor after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human FLT3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of human FMS using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of human FGFR3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human BTK using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of human ALK using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human CHK2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 241nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 246nMAssay Description:Inhibition of human PDGFRalpha using ATP as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 256nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 271nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cephalon, Inc.
Curated by ChEMBL
Cephalon, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Erg expressed CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
