Compile Data Set for Download or QSAR

Found 32 hits of Enzyme Inhibition Constant Data   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Inhibition of wild type EGFR using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379218(CHEMBL2011304)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of wild type B-Raf using MEK1-KM as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379214(CHEMBL2011291 | US9416123, 6)copy SMILEScopy InChI
Affinity DataIC50: 399nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379227(CHEMBL2011293 | US9416123, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379224(CHEMBL2011297 | US9416123, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379225(CHEMBL2011295 | US9416123, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379226(CHEMBL2011294 | US9416123, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379218(CHEMBL2011304)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379223(CHEMBL2011298 | US9416123, 12)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379228(CHEMBL2011292 | US9416123, 5)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379216(CHEMBL2011296 | US9416123, 10)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379222(CHEMBL2011299 | US9416123, 14)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379223(CHEMBL2011298 | US9416123, 12)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379217(CHEMBL2011305 | US9416123, 20)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379215(CHEMBL2011301 | US9416123, 18)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379227(CHEMBL2011293 | US9416123, 7)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379226(CHEMBL2011294 | US9416123, 8)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379217(CHEMBL2011305 | US9416123, 20)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379222(CHEMBL2011299 | US9416123, 14)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379220(CHEMBL2011302 | US9416123, 16)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379215(CHEMBL2011301 | US9416123, 18)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379228(CHEMBL2011292 | US9416123, 5)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379216(CHEMBL2011296 | US9416123, 10)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379220(CHEMBL2011302 | US9416123, 16)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379225(CHEMBL2011295 | US9416123, 9)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379221(CHEMBL2011300 | US9416123, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379224(CHEMBL2011297 | US9416123, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379221(CHEMBL2011300 | US9416123, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8N18PubMed
* indicates data uncertainty>20%