Compile Data Set for Download or QSAR

Found 32 hits of Enzyme Inhibition Constant Data   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Inhibition of AXLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  85nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibition of cMETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of PDGFR-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  220nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  280nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of FGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of ABLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataKi:  770nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355489(CHEMBL1835867)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355489(CHEMBL1835867)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of SCF-induced phosphorylation of c-KIT in human TF1 cells after 1 hr by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355491(CHEMBL1835870)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of c-KIT-mediated ERK 1/2 phosphorylation in human TF1 cells at 4 to 12 nM after 1 hr by immunoblot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355480(CHEMBL1835747)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355480(CHEMBL1835747)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355482(CHEMBL1835749)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355482(CHEMBL1835749)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355468(CHEMBL1835743)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355467(CHEMBL1833992)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant FLT3 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355468(CHEMBL1835743)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355479(CHEMBL1835746)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50355467(CHEMBL1833992)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant c-Kit by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6Z6RPubMed
* indicates data uncertainty>20%