Found 53 hits of Enzyme Inhibition Constant Data
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]PGD2 from CRTH2 expressed in HEK293 cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in K562 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]PGD2 from CRTH2 expressed in CHO cells after 1 hr by beta counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in K562 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:Displacement of [3H]PGD2 from CRTH2 expressed in CHO cells after 1 hr by beta counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of TP receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of CRTH2More data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in HEK293 cells after 90 mins by TopCount analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in HEK293 cells after 90 mins by TopCount analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in HEK293 cells after 90 mins by TopCount analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 expressed in HEK293 cells after 2 hrs by microbetascintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]PGD2 from recombinant human CRTH2 expressed in HEK293 cells after 2 hrs by microbetascintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CRTH2 expressed in Th2 cells assessed as inhibition of PGD2-induced IL13 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in K562 cells after 60 mins by scintillation counting in presence of 4% human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at CRTH2 expressed in Th2 cells assessed as inhibition of PGD2-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at CRTH2 expressed in Th2 cells assessed as inhibition of PGD2-induced antiapoptotic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antagonist activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced shape change by gated autofluorescence forward scatter analy...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of rat aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 343nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of rat aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 626nMAssay Description:Antagonist activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced shape change by gated autofluorescence forward scatter analy...More data for this Ligand-Target Pair
Affinity DataIC50: 812nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair