Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50359991(CHEMBL1927953)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50359991(CHEMBL1927953)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50359991(CHEMBL1927953)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384887(CHEMBL2035569)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384887(CHEMBL2035569)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384886(CHEMBL2035568)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384886(CHEMBL2035568)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50247012(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Inhibition of mouse 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384887(CHEMBL2035569)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384886(CHEMBL2035568)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384887(CHEMBL2035569)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50384886(CHEMBL2035568)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M090QPubMed
* indicates data uncertainty>20%