Compile Data Set for Download or QSAR

Found 19 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388189(CHEMBL2057918)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Competitive inhibition of BTK by TR-FRET based competitive assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BLKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388185(CHEMBL2057919)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of BMXMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388190(CHEMBL2057923)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)copy SMILEScopy InChI
Affinity DataIC50: 1.93nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388181(CHEMBL2057913)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388183(CHEMBL2057915)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388180(CHEMBL2057912)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388185(CHEMBL2057919)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK in human Ramos cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388186(CHEMBL2057920)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388184(CHEMBL2057916)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388188(CHEMBL2057922)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388187(CHEMBL2057921)copy SMILEScopy InChI
Affinity DataIC50: 144nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50388182(CHEMBL2057914)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human BTK by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)copy SMILEScopy InChI
Affinity DataIC50: 624nMAssay Description:Inhibition of LYNMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM24941((2Z)-2-{[(2,5-dibromophenyl)amino](hydroxy)methyli...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant BTK expressed in baculovirus expression vector systemMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KMFPubMed
* indicates data uncertainty>20%