Compile Data Set for Download or QSAR

Found 68 hits of Enzyme Inhibition Constant Data   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389803(AZD7762 | CHEMBL2041933)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389817(CHEMBL2070702)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389806(CHEMBL2070714)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50243049((S)-1-(5-(4-cyanophenyl)-3-(piperidin-3-ylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50243258((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389804(CHEMBL2070716)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389815(CHEMBL2070704)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389805(CHEMBL2070715)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50242824((S)-1-(5-(4-fluorophenyl)-3-(piperidin-3-ylcarbamo...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50242822(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(2-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389813(CHEMBL2070706)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389822(CHEMBL2070697)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389803(AZD7762 | CHEMBL2041933)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CHK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389823(CHEMBL2070707)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50242823(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389814(CHEMBL2070705)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389811(CHEMBL2070709)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50242893(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-chlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389812(CHEMBL2070708)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389820(CHEMBL2070699)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389809(CHEMBL2070711)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389810(CHEMBL2070710)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389808(CHEMBL2070712)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant CHK1 expressed in insect cells using biotinylaminohexanoyl-KKVSRSGLYRSPMPENLNRPR as substrate after 2 hrs by scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389803(AZD7762 | CHEMBL2041933)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389803(AZD7762 | CHEMBL2041933)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389810(CHEMBL2070710)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50242822(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(2-fluorophen...)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389805(CHEMBL2070715)copy SMILEScopy InChI
Affinity DataEC50: >1.30E+4nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389804(CHEMBL2070716)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389817(CHEMBL2070702)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389822(CHEMBL2070697)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50243258((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389823(CHEMBL2070707)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389815(CHEMBL2070704)copy SMILEScopy InChI
Affinity DataEC50:  700nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389808(CHEMBL2070712)copy SMILEScopy InChI
Affinity DataEC50:  200nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389805(CHEMBL2070715)copy SMILEScopy InChI
Affinity DataEC50:  940nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389820(CHEMBL2070699)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389806(CHEMBL2070714)copy SMILEScopy InChI
Affinity DataEC50:  600nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389812(CHEMBL2070708)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389809(CHEMBL2070711)copy SMILEScopy InChI
Affinity DataEC50:  5.70E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389803(AZD7762 | CHEMBL2041933)copy SMILEScopy InChI
Affinity DataEC50:  280nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389817(CHEMBL2070702)copy SMILEScopy InChI
Affinity DataEC50:  1.30E+4nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389806(CHEMBL2070714)copy SMILEScopy InChI
Affinity DataEC50:  30nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389822(CHEMBL2070697)copy SMILEScopy InChI
Affinity DataEC50:  590nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50243258((S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophe...)copy SMILEScopy InChI
Affinity DataEC50:  450nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389810(CHEMBL2070710)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389809(CHEMBL2070711)copy SMILEScopy InChI
Affinity DataEC50:  150nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389813(CHEMBL2070706)copy SMILEScopy InChI
Affinity DataEC50:  60nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50242823(1-(3-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophen...)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of campothecin induced check pointMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50389820(CHEMBL2070699)copy SMILEScopy InChI
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as check point abrogationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0PR6PubMed
Displayed 1 to 50 (of 68 total ) | Next | Last >>* indicates data uncertainty>20%