Compile Data Set for Download or QSAR

Found 40 hits of Enzyme Inhibition Constant Data   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391953(CHEMBL2152288)copy SMILEScopy InChI
Affinity DataIC50: 1.67nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391978(CHEMBL2152287)copy SMILEScopy InChI
Affinity DataIC50: 2.97nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391977(CHEMBL2152286)copy SMILEScopy InChI
Affinity DataIC50: 4.62nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391950(CHEMBL2152289)copy SMILEScopy InChI
Affinity DataIC50: 5.41nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391974(CHEMBL2152283)copy SMILEScopy InChI
Affinity DataIC50: 8.36nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391976(CHEMBL2152285)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391973(CHEMBL2152282)copy SMILEScopy InChI
Affinity DataIC50: 13.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391971(CHEMBL2152280)copy SMILEScopy InChI
Affinity DataIC50: 18.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391968(CHEMBL2152277)copy SMILEScopy InChI
Affinity DataIC50: 22.2nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391963(CHEMBL2152272)copy SMILEScopy InChI
Affinity DataIC50: 22.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391965(CHEMBL2152274)copy SMILEScopy InChI
Affinity DataIC50: 25.0nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391962(CHEMBL2152271)copy SMILEScopy InChI
Affinity DataIC50: 26.5nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391961(CHEMBL2152270)copy SMILEScopy InChI
Affinity DataIC50: 31.4nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391966(CHEMBL2152275)copy SMILEScopy InChI
Affinity DataIC50: 33.2nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391975(CHEMBL2152284)copy SMILEScopy InChI
Affinity DataIC50: 33.8nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391964(CHEMBL2152273)copy SMILEScopy InChI
Affinity DataIC50: 34.3nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391955(CHEMBL2152264)copy SMILEScopy InChI
Affinity DataIC50: 42.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391970(CHEMBL2152279)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391967(CHEMBL2152276)copy SMILEScopy InChI
Affinity DataIC50: 53.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391972(CHEMBL2152281)copy SMILEScopy InChI
Affinity DataIC50: 64.7nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391960(CHEMBL2152269)copy SMILEScopy InChI
Affinity DataIC50: 69.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391969(CHEMBL2152278)copy SMILEScopy InChI
Affinity DataIC50: 88.6nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391951(CHEMBL2152290)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391953(CHEMBL2152288)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of KIT by high throughput binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391952(CHEMBL2152291)copy SMILEScopy InChI
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391957(CHEMBL2152266)copy SMILEScopy InChI
Affinity DataKd:  88nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50332020(CHEMBL1289468 | N-(3-(3-(3,4-dimethoxyphenyl)-1H-p...)copy SMILEScopy InChI
Affinity DataKd:  2.30E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391954(CHEMBL2152262)copy SMILEScopy InChI
Affinity DataKd:  125nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391955(CHEMBL2152264)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391959(CHEMBL2152268)copy SMILEScopy InChI
Affinity DataKd:  110nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)copy SMILEScopy InChI
Affinity DataKd:  75nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)copy SMILEScopy InChI
Affinity DataKd:  58nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50332012(CHEMBL1290790 | N-(5-(3-(3,4-dimethoxyphenyl)-1H-p...)copy SMILEScopy InChI
Affinity DataKd:  48nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391955(CHEMBL2152264)copy SMILEScopy InChI
Affinity DataKd:  16nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50332020(CHEMBL1289468 | N-(3-(3-(3,4-dimethoxyphenyl)-1H-p...)copy SMILEScopy InChI
Affinity DataKd:  91nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50332012(CHEMBL1290790 | N-(5-(3-(3,4-dimethoxyphenyl)-1H-p...)copy SMILEScopy InChI
Affinity DataKd:  145nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391959(CHEMBL2152268)copy SMILEScopy InChI
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)copy SMILEScopy InChI
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391958(CHEMBL2152267)copy SMILEScopy InChI
Affinity DataKd:  270nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50332019(5-(3-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridi...)copy SMILEScopy InChI
Affinity DataKd:  960nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
* indicates data uncertainty>20%