Compile Data Set for Download or QSAR

Found 4 hits of Enzyme Inhibition Constant Data   

TargetGTPase NRas(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50421183(CHEMBL2086789)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of N-Ras expressed in Escherichia coli using [3H]GDP and [3H]GTP assessed as inhibition of intrinsic nucleotide exchange by scintillation ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20JZPubMed
TargetSon of sevenless homolog 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition to His6-tagged Sos1 catalytic domain-mediated nucleotide exchange by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20JZPubMed
TargetGTPase HRas(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)copy SMILEScopy InChI
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to His6-tagged HRas expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20JZPubMed
TargetGTPase HRas(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50421182(CHEMBL2086797)copy SMILEScopy InChI
Affinity DataKd:  1.58E+5nMAssay Description:Binding affinity to His6-tagged HRas-GDP expressed in Escherichia coli (BL21) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR20JZPubMed
* indicates data uncertainty>20%