Found 26 hits of Enzyme Inhibition Constant Data
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 147nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 254nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Eisai Co., Ltd.
Curated by ChEMBL
Eisai Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2 receptor assessed as inhibition of CRF-induced intracellular cAMP accumulationMore data for this Ligand-Target Pair