Compile Data Set for Download or QSAR

Found 26 hits of Enzyme Inhibition Constant Data   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398565(CHEMBL2179195)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Antagonist activity at CRF1 receptor in human IMR32 cells assessed as inhibition of CRF-induced intracellular cAMP accumulation after 30 mins by immu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398579(CHEMBL2179182)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398587(CHEMBL2179197 | US8530504, 4)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398566(CHEMBL2179196)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398580(CHEMBL2179181)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398578(CHEMBL2179183 | US8530504, 27)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398582(CHEMBL2179179)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398573(CHEMBL2179188)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398583(CHEMBL2179178)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398568(CHEMBL2179193)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398570(CHEMBL2179191)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398585(CHEMBL2179176)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398565(CHEMBL2179195)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398581(CHEMBL2179180)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398586(CHEMBL2177105 | US8530504, 5)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398574(CHEMBL2179187)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398571(CHEMBL2179190)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398575(CHEMBL2179186)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398577(CHEMBL2179184)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398569(CHEMBL2179192)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398572(CHEMBL2179189)copy SMILEScopy InChI
Affinity DataIC50: 136nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398576(CHEMBL2179185)copy SMILEScopy InChI
Affinity DataIC50: 147nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398584(CHEMBL2179177)copy SMILEScopy InChI
Affinity DataIC50: 223nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398567(CHEMBL2179194)copy SMILEScopy InChI
Affinity DataIC50: 254nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Eisai Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50398565(CHEMBL2179195)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2 receptor assessed as inhibition of CRF-induced intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD202PPubMed
* indicates data uncertainty>20%