Compile Data Set for Download or QSAR

Found 21 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401389(CHEMBL2206441)copy SMILEScopy InChI
Affinity DataKi:  5.01E+3nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401387(CHEMBL2206445)copy SMILEScopy InChI
Affinity DataKi: >8.50E+3nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401385(CHEMBL2206447)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401386(CHEMBL2206446)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401387(CHEMBL2206445)copy SMILEScopy InChI
Affinity DataIC50: 9.23nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401388(CHEMBL2206442)copy SMILEScopy InChI
Affinity DataIC50: 11.2nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401389(CHEMBL2206441)copy SMILEScopy InChI
Affinity DataIC50: 11.2nMAssay Description:Displacement of [3H]JNJ-40068782 from human mGLuR2 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401389(CHEMBL2206441)copy SMILEScopy InChI
Affinity DataEC50:  8.20nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401395(CHEMBL2206440)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401387(CHEMBL2206445)copy SMILEScopy InChI
Affinity DataEC50:  7.5nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401394(CHEMBL2206443)copy SMILEScopy InChI
Affinity DataEC50:  37nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401390(CHEMBL2206437)copy SMILEScopy InChI
Affinity DataEC50:  61.7nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401385(CHEMBL2206447)copy SMILEScopy InChI
Affinity DataEC50:  6.90nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401393(CHEMBL2206444)copy SMILEScopy InChI
Affinity DataEC50:  26nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401386(CHEMBL2206446)copy SMILEScopy InChI
Affinity DataEC50:  9.30nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50399099(CHEMBL2179333)copy SMILEScopy InChI
Affinity DataEC50:  56.2nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401392(CHEMBL2206448)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401391(CHEMBL2206449)copy SMILEScopy InChI
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401396(CHEMBL2206439)copy SMILEScopy InChI
Affinity DataEC50:  10.5nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401397(CHEMBL2206438)copy SMILEScopy InChI
Affinity DataEC50:  31nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen-Cilag S.A.

Curated by ChEMBL
LigandPNGBDBM50401388(CHEMBL2206442)copy SMILEScopy InChI
Affinity DataEC50:  6nMAssay Description:Agonist activity at human mGLuR2 expressed in CHO cell membrane assessed as [32S]GTPgammaS after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9XSSPubMed
* indicates data uncertainty>20%