Compile Data Set for Download or QSAR

Found 12 hits of Enzyme Inhibition Constant Data   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:The method for determination of Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzy...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMpH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataIC50: 5.55E+3nMAssay Description:The method for determination of Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzy...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMpH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238310(2-((dimethylamino)methyl)-4,5-dimethylphenol (2a))copy SMILEScopy InChI
Affinity DataIC50: 6.95E+3nMAssay Description:The method for determination of Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238309(3,4-Dimethylphenol (1))copy SMILEScopy InChI
Affinity DataIC50: 4.13E+4nMAssay Description:The method for determination of Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238309(3,4-Dimethylphenol (1))copy SMILEScopy InChI
Affinity DataIC50: 4.91E+4nMAssay Description:The method for determination of Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238311(2-((dibenzylamino)methyl)-4,5-dimethylphenol (2e))copy SMILEScopy InChI
Affinity DataIC50: 5.77E+4nMAssay Description:The method for determination of Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238311(2-((dibenzylamino)methyl)-4,5-dimethylphenol (2e))copy SMILEScopy InChI
Affinity DataIC50: 4.40E+5nMpH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238310(2-((dimethylamino)methyl)-4,5-dimethylphenol (2a))copy SMILEScopy InChI
Affinity DataIC50: 8.80E+5nMpH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238309(3,4-Dimethylphenol (1))copy SMILEScopy InChI
Affinity DataIC50: 9.30E+5nMpH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Dumlupinar University

LigandPNGBDBM238309(3,4-Dimethylphenol (1))copy SMILEScopy InChI
Affinity DataIC50: 1.03E+6nMpH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5DZ8PubMed
* indicates data uncertainty>20%