Affinity Data by PubMed id=23249297

Found 75 hits of Enzyme Inhibition Constant Data

Aurora kinase A(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 100nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase B(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 500nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 600nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Angiopoietin-1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 600nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 600nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 700nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 700nMAssay Description:Inhibition of SAK (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Hepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 800nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Angiopoietin-1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 800nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 1.00E+3nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Hepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.10E+3nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.20E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.30E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase A(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428740(Bastadin 16 | CHEMBL2333164)copy SMILEScopy InChI

IC50: 1.30E+3nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Mitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 1.30E+3nMAssay Description:Inhibition of COT (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 1.30E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Insulin receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 1.40E+3nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Cyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 1.40E+3nMAssay Description:Inhibition of CDK4/cyclin-D1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 1.40E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Cyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.50E+3nMAssay Description:Inhibition of CDK4/cyclin-D1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 1.50E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 1.60E+3nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Mitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.60E+3nMAssay Description:Inhibition of COT (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.60E+3nMAssay Description:Inhibition of CDK2/cyclin-A (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase B(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428740(Bastadin 16 | CHEMBL2333164)copy SMILEScopy InChI

IC50: 1.60E+3nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase A(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50241984(BASTADIN 6 | CHEMBL505907 | bastadin-6)copy SMILEScopy InChI

IC50: 1.70E+3nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

NUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 1.70E+3nMAssay Description:Inhibition of ARK5 (unknown origin)More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 1.70E+3nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

NUAK family SNF1-like kinase 1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.80E+3nMAssay Description:Inhibition of ARK5 (unknown origin)More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Angiopoietin-1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 1.80E+3nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

RAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.90E+3nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 1.90E+3nMAssay Description:Inhibition of SAK (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 1.90E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 2.00E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50241984(BASTADIN 6 | CHEMBL505907 | bastadin-6)copy SMILEScopy InChI

IC50: 2.00E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Focal adhesion kinase 1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 2.10E+3nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 2.10E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 2.10E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 2.30E+3nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase B(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 2.30E+3nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 2.40E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase B(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 2.60E+3nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase A(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428738(CHEMBL2333163 | Sesquibastadin 1)copy SMILEScopy InChI

IC50: 2.60E+3nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Cyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 2.60E+3nMAssay Description:Inhibition of CDK4/cyclin-D1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 2.80E+3nMAssay Description:Inhibition of VEGFR3 (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Hepatocyte growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 2.80E+3nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50150778(Bastadin-7 | Bastadins 7 | CHEMBL360190 | bastadin...)copy SMILEScopy InChI

IC50: 2.80E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428740(Bastadin 16 | CHEMBL2333164)copy SMILEScopy InChI

IC50: 2.90E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Insulin receptor(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50428737(BASTADIN 3)copy SMILEScopy InChI

IC50: 2.90E+3nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Aurora kinase B(Homo sapiens (Human))
Heinrich-Heine University

Curated by ChEMBL

BDBM50241984(BASTADIN 6 | CHEMBL505907 | bastadin-6)copy SMILEScopy InChI

IC50: 2.90E+3nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q21N82F5PubMed

Displayed 1 to 50 (of 75 total ) | Next | Last >>* indicates data uncertainty>20%

Targets 23 ▿
- Aurora kinase B 5
- Aurora kinase A 5
- Receptor tyrosine-protein kinase erbB-2 5
- Epidermal growth factor receptor 5
- Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 5
- Receptor-type tyrosine-protein kinase FLT3 4
- Mitogen-activated protein kinase kinase kinase 8 4
- Angiopoietin-1 receptor 3
- Ephrin type-B receptor 4 3
- Serine/threonine-protein kinase PLK4 3
- Hepatocyte growth factor receptor 3
- Platelet-derived growth factor receptor beta 3
- Insulin-like growth factor 1 receptor 3
- Proto-oncogene tyrosine-protein kinase Src 3
- Insulin receptor 3
- Vascular endothelial growth factor receptor 2 3
- Vascular endothelial growth factor receptor 3 3
- Focal adhesion kinase 1 3
- NUAK family SNF1-like kinase 1 3
- Serine/threonine-protein kinase PLK1 2
- Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 2
- Casein kinase II subunit alpha 1
- RAC-alpha serine/threonine-protein kinase 1
Publications 1 ▿
- J Nat Prod 76: 121-5 (2013) 75
Institutions 1 ▿
- [Heinrich-Heine University] 75
Affinity: 1.0E+2 to 1.0E+4 nM▿
- IC50 75
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0