Compile Data Set for Download or QSAR

Found 38 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Inhibition of Abl (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Src (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Lck (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of EphB4 (unknown origin) using [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of EphB4 (unknown origin) using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of Src (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428743(CHEMBL2333603)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428743(CHEMBL2333603)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428742(CHEMBL2333595)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428743(CHEMBL2333603)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of Src (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428743(CHEMBL2333603)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428742(CHEMBL2333595)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428742(CHEMBL2333595)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Src (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299218(8-(2-Methoxyphenyl)-1-methyl-7-(2'-methyl-5'-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)copy SMILEScopy InChI
Affinity DataIC50: 133nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428742(CHEMBL2333595)copy SMILEScopy InChI
Affinity DataIC50: 139nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of Yes1 (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428744(CHEMBL2333593)copy SMILEScopy InChI
Affinity DataIC50: 177nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428746(CHEMBL2333597)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)copy SMILEScopy InChI
Affinity DataIC50: 203nMAssay Description:Inhibition of Abl (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428744(CHEMBL2333593)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428741(CHEMBL2333602)copy SMILEScopy InChI
Affinity DataIC50: 264nMAssay Description:Inhibition of Lck (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428746(CHEMBL2333597)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428743(CHEMBL2333603)copy SMILEScopy InChI
Affinity DataIC50: 284nMAssay Description:Inhibition of Yes1 (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428747(CHEMBL2333600)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428743(CHEMBL2333603)copy SMILEScopy InChI
Affinity DataIC50: 493nMAssay Description:Inhibition of Lck (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428742(CHEMBL2333595)copy SMILEScopy InChI
Affinity DataIC50: 496nMAssay Description:Inhibition of Yes1 (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50374167(CHEMBL271967)copy SMILEScopy InChI
Affinity DataIC50: 538nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428743(CHEMBL2333603)copy SMILEScopy InChI
Affinity DataIC50: 578nMAssay Description:Inhibition of Abl (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428742(CHEMBL2333595)copy SMILEScopy InChI
Affinity DataIC50: 617nMAssay Description:Inhibition of Lck (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428742(CHEMBL2333595)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of Abl (unknown origin) using [gamma-33P]ATP after 30 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428745(CHEMBL2333594)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50374167(CHEMBL271967)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50428747(CHEMBL2333600)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human myc-tagged full length EphB4 expressed in MEF cells assessed as inhibition of ephrinB2-Fc-induced autophosphorylation incubated f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299226(8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using Z'-LYTE TYR-1 peptide as substrate after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299226(8-(2-methoxyphenyl)-1-methyl-7-phenyl-1H-imidazo[1...)copy SMILEScopy InChI
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of EphB4 (unknown origin) transfected in CHO cells using [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K1SPubMed
* indicates data uncertainty>20%