Compile Data Set for Download or QSAR

Found 44 hits of Enzyme Inhibition Constant Data   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430292(CHEMBL2333441)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430298(CHEMBL2333434)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430299(CHEMBL2333433)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430290(CHEMBL2333443)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430294(CHEMBL2333439)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430297(CHEMBL2333436)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 5 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430293(CHEMBL2333440)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 1000 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430300(CHEMBL2333432)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430291(CHEMBL2333442)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetAurora kinase B(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 1000 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of intracellular FAK autophosphorylation in human PC3 M-luc cells after 2 hrsMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Pyk2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Pyk2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetAurora kinase B(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Pyk2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetAurora kinase B(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of aurora-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430287(CHEMBL2333444)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430289(CHEMBL2333445)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Akt1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430292(CHEMBL2333441)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of intracellular FAK autophosphorylation in human PC3 M-luc cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430295(CHEMBL2333438)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430291(CHEMBL2333442)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of intracellular FAK autophosphorylation in human PC3 M-luc cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430290(CHEMBL2333443)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of intracellular FAK autophosphorylation in human PC3 M-luc cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430296(CHEMBL2333437)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
* indicates data uncertainty>20%