Compile Data Set for Download or QSAR

Found 20 hits of Enzyme Inhibition Constant Data   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50173715((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50295296(CHEMBL539470 | cis-3-((1R,2S)-2-((dimethylamino)me...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491389(CHEMBL2380980)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491388(CHEMBL2380975)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491392(CHEMBL2380983)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491395(CHEMBL2380971)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491396(CHEMBL2380979)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491394(CHEMBL2380974)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491398(CHEMBL2380976)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491390(CHEMBL2380978)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491399(CHEMBL2380973)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491391(CHEMBL2380981)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491397(CHEMBL2380977)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491388(CHEMBL2380975)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491393(CHEMBL2380982)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491388(CHEMBL2380975)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491389(CHEMBL2380980)copy SMILEScopy InChI
Affinity DataIC50: 8.20E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC42G4PubMed
* indicates data uncertainty>20%