Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Displacement of [125I]substance P from human NK1 receptor expressed in CHO cells in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277511(3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Binding affinity to human NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Binding affinity to human NK3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Binding affinity to human NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50437205(CHEMBL2402572)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1N9JPubMed
* indicates data uncertainty>20%