Compile Data Set for Download or QSAR

Found 100 hits of Enzyme Inhibition Constant Data   

LigandPNGBDBM50438224(CHEMBL2407759)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438223(CHEMBL2407758)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438224(CHEMBL2407759)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
LigandPNGBDBM50438223(CHEMBL2407758)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438219(CHEMBL2407761)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438222(CHEMBL2407757)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438221(CHEMBL2407760)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438222(CHEMBL2407757)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438211(CHEMBL2407795)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438220(CHEMBL2407792)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438221(CHEMBL2407760)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438173(CHEMBL2407966)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438220(CHEMBL2407792)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438218(CHEMBL2407767)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438212(CHEMBL2407787)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438213(CHEMBL2407777)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438217(CHEMBL2407763)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438219(CHEMBL2407761)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438218(CHEMBL2407767)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438214(CHEMBL2407779)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438217(CHEMBL2407763)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438216(CHEMBL2407961)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438206(CHEMBL2407772)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438215(CHEMBL2407965)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438213(CHEMBL2407777)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438214(CHEMBL2407779)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438208(CHEMBL2407793)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438204(CHEMBL2407958)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438185(CHEMBL2407770)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438212(CHEMBL2407787)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438196(CHEMBL2407781)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438211(CHEMBL2407795)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438210(CHEMBL2407962)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438189(CHEMBL2407098)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438209(CHEMBL2407959)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438198(CHEMBL2407785)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438208(CHEMBL2407793)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438182(CHEMBL2407771)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438207(CHEMBL2407960)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438206(CHEMBL2407772)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438205(CHEMBL2407778)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438201(CHEMBL2407762)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438187(CHEMBL2407769)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438193(CHEMBL2407775)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438179(CHEMBL2407789)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438200(CHEMBL2407791)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438204(CHEMBL2407958)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
LigandPNGBDBM50438225(CHEMBL2407766)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438201(CHEMBL2407762)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
OSI Pharmaceuticals LLC

Curated by ChEMBL
LigandPNGBDBM50438181(CHEMBL2407788)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J2KPubMed
Displayed 1 to 50 (of 100 total ) | Next | Last >>* indicates data uncertainty>20%