Compile Data Set for Download or QSAR

Found 34 hits of Enzyme Inhibition Constant Data   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443182(CHEMBL3086538)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443181(CHEMBL3086535)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443180(CHEMBL3086536)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443178(CHEMBL3086537)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443177(CHEMBL3086533)copy SMILEScopy InChI
Affinity DataKi:  2.5nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443189(CHEMBL3086327)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443188(CHEMBL3086329)copy SMILEScopy InChI
Affinity DataKi:  6.40nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443187(CHEMBL3086328)copy SMILEScopy InChI
Affinity DataKi:  6.60nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443175(CHEMBL3086534)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443186(CHEMBL3086331)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443185(CHEMBL3086330)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443184(CHEMBL3086544)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443183(CHEMBL3086545)copy SMILEScopy InChI
Affinity DataKi:  85nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443194(CHEMBL3086542)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443193(CHEMBL3086540)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443192(CHEMBL3086539)copy SMILEScopy InChI
Affinity DataKi:  460nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443179(CHEMBL3086332)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443191(CHEMBL3086541)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443190(CHEMBL3086543)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443176(CHEMBL3086326)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of full length GST-tagged ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443182(CHEMBL3086538)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443181(CHEMBL3086535)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443180(CHEMBL3086536)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443178(CHEMBL3086537)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443175(CHEMBL3086534)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443188(CHEMBL3086329)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443177(CHEMBL3086533)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443187(CHEMBL3086328)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443183(CHEMBL3086545)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443186(CHEMBL3086331)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443185(CHEMBL3086330)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443176(CHEMBL3086326)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443184(CHEMBL3086544)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Evotec (UK) Ltd

Curated by ChEMBL
LigandPNGBDBM50443189(CHEMBL3086327)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as inhibition of PLC-gamma1 phosphorylation by immuno-detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4D16PubMed
* indicates data uncertainty>20%