Compile Data Set for Download or QSAR

Found 16 hits of Enzyme Inhibition Constant Data   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 42nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 114nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107675(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)copy SMILEScopy InChI
Affinity DataIC50: 142nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107677(1-(3-Chloro-4-fluorophenyl)-3-(3-(methyl (2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 232nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107675(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)copy SMILEScopy InChI
Affinity DataIC50: 271nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107673(1-(3-(6-Chloro-2-methylpyrimidin-4-ylamino)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 298nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107677(1-(3-Chloro-4-fluorophenyl)-3-(3-(methyl (2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 366nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107674(1-(3-Chloro-4-fluorophenyl)-3-(3-(2-methyl- 6-morp...)copy SMILEScopy InChI
Affinity DataIC50: 626nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107673(1-(3-(6-Chloro-2-methylpyrimidin-4-ylamino)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 722nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107674(1-(3-Chloro-4-fluorophenyl)-3-(3-(2-methyl- 6-morp...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107678(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107678(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107679(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 4.99E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107679(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(methy...)copy SMILEScopy InChI
Affinity DataIC50: 5.28E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107676(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)copy SMILEScopy InChI
Affinity DataIC50: 7.17E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107676(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
* indicates data uncertainty>20%