Found 2 hits of Enzyme Inhibition Constant Data
Affinity DataIC50: 0.100nMAssay Description:Inhibition of rhesus monkey brain PDE2A3 using FAM-labeled cAMP as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Dart Neuroscience LLC
Curated by ChEMBL
Dart Neuroscience LLC
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant rat PDE10A expressed in baculovirus infected insect SF9 cells using [3H]-cAMP as substrate after 60 mins by scintillation p...More data for this Ligand-Target Pair