Compile Data Set for Download or QSAR

Found 34 hits of Enzyme Inhibition Constant Data   

TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM86478(A-317491)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(RAT)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Antagonist activity at recombinant rat P2X1 receptor expressed in Xenopus oocytes assessed as ion flux stimulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444434(CHEMBL3091630)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM86478(A-317491)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Antagonist activity at recombinant human P2X3 receptor transfected in human 1321N1 cells assessed as inhibition of alpha, beta me-ATP-induced current...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Antagonist activity at mouse P2X1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444431(CHEMBL3091628)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced accumulation of ethidium+ after 120 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Antagonist activity at recombinant human P2X7 receptor assessed as inhibition of BzATP-mediated Yo-Pro uptake measured for 1 hr by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human P2X3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444432(CHEMBL3091610)copy SMILEScopy InChI
Affinity DataIC50: 267nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444427(CHEMBL3091631)copy SMILEScopy InChI
Affinity DataIC50: 366nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444433(CHEMBL3091632)copy SMILEScopy InChI
Affinity DataIC50: 377nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444425(CHEMBL3091607)copy SMILEScopy InChI
Affinity DataIC50: 446nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444432(CHEMBL3091610)copy SMILEScopy InChI
Affinity DataIC50: 458nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444425(CHEMBL3091607)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444435(CHEMBL3091619)copy SMILEScopy InChI
Affinity DataIC50: 474nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444429(CHEMBL3091620)copy SMILEScopy InChI
Affinity DataIC50: 587nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444421(CHEMBL3091629)copy SMILEScopy InChI
Affinity DataIC50: 636nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444424(CHEMBL3091633)copy SMILEScopy InChI
Affinity DataIC50: 638nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444420(CHEMBL3091605)copy SMILEScopy InChI
Affinity DataIC50: 645nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444428(CHEMBL3091635)copy SMILEScopy InChI
Affinity DataIC50: 652nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444419(CHEMBL3091625)copy SMILEScopy InChI
Affinity DataIC50: 723nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444418(CHEMBL3091606)copy SMILEScopy InChI
Affinity DataIC50: 768nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444420(CHEMBL3091605)copy SMILEScopy InChI
Affinity DataIC50: 797nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444426(CHEMBL3091618)copy SMILEScopy InChI
Affinity DataIC50: 824nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444423(CHEMBL3091634)copy SMILEScopy InChI
Affinity DataIC50: 856nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444418(CHEMBL3091606)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444422(CHEMBL3091627)copy SMILEScopy InChI
Affinity DataIC50: 928nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444417(CHEMBL3091622)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Antagonist activity at recombinant human P2X7 receptor assessed as inhibition of BzATP-mediated Yo-Pro uptake measured for 1 hr by FLIPR assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444430(CHEMBL3091617)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444416(CHEMBL3091623)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50444415(CHEMBL3091621)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61MQHPubMed
* indicates data uncertainty>20%