Found 34 hits of Enzyme Inhibition Constant Data
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at recombinant rat P2X1 receptor expressed in Xenopus oocytes assessed as ion flux stimulationMore data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Antagonist activity at recombinant human P2X3 receptor transfected in human 1321N1 cells assessed as inhibition of alpha, beta me-ATP-induced current...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Antagonist activity at mouse P2X1 receptorMore data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced accumulation of ethidium+ after 120 mins...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Antagonist activity at recombinant human P2X7 receptor assessed as inhibition of BzATP-mediated Yo-Pro uptake measured for 1 hr by FLIPR assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human P2X3 receptorMore data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 267nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 366nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 377nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 446nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 458nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 474nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 587nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 636nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 638nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 645nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 652nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 723nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 768nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 797nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 824nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 856nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 928nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Antagonist activity at recombinant human P2X7 receptor assessed as inhibition of BzATP-mediated Yo-Pro uptake measured for 1 hr by FLIPR assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 2.93E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Gwangju Institute of Science and Technology (GIST)
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair